| Duke Scleroderma Clinic Patient Registry (NCT02851875) | Duke University | 2016-04-01 |
| Seoul National University Hospital Systemic Sclerosis Cohort (NCT02819947) | Seoul National University Hospital | 2016-03-01 |
| Comparing and Combining Bortezomib and Mycophenolate in SSc Pulmonary Fibrosis (NCT02370693) | Northwestern University | 2016-03-01 |
| Itch and Clinacal Caracteristics in Systemic Sclerosis (NCT03297580) | University Hospital, Brest | 2016-02-01 |
| Systemic Sclerosis Clinical and Biomarker Study (NCT02531009) | Biogen | 2015-12-01 |
| A Study of the Efficacy and Safety of Tocilizumab in Participants With Systemic Sclerosis (SSc) (NCT02453256) | Hoffmann-La Roche | 2015-11-20 |
| Topical Rosemary Oil Application in Systemic Sclerosis (NCT03531216) | ARCIM Institute Academic Research in Complementary and Integrative Medicine | 2015-11-02 |
| CSL Behring Sclero XIII (NCT02551042) | University College, London | 2015-09-01 |
| Safety Of Fat Micrografts With Adipose-Derived Stromal Vascular Fraction In Hands Of Patients With Systemic Sclerosis (NCT04387825) | Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran | 2015-08-13 |
| Effectiveness of Saccharomyces Boulardii for Gastrointestinal Bacterial-overgrowth in Systemic Sclerosis (NCT03692299) | Coordinación de Investigación en Salud, Mexico | 2015-06-01 |
| Scleroderma Treatment With Celution Processed Adipose Derived Regenerative Cells (STAR) (NCT02396238) | Cytori Therapeutics | 2015-05-15 |
| Evaluating Pulmonary Arterial Hypertension in Patients With Systemic Sclerosis (NCT02339961) | Echosense Ltd. | 2015-02-01 |
| Treatment of Digital Ulcers in Korean Patients With Systemic Sclerosis: a Prospective Cohort Study (NCT02642146) | Seoul National University Hospital | 2015-01-01 |
| Long Term Effect of Buspirone on Esophageal Function and Esophageal Symptoms in Patients With Systematic Sclerosis (SSc) (NCT02363478) | Laikο General Hospital, Athens | 2014-12-01 |
| Endothelial Microparticles in Systemic Sclerosis Pulmonary Hypertension (NCT02331225) | Louisiana State University Health Sciences Center in New Orleans | 2014-12-01 |
| Effects of Probiotics on Gastrointestinal Symptoms and on the Immune System in Patients With Systemic Sclerosis (NCT02302352) | Federal University of São Paulo | 2014-12-01 |
| Evaluation of Pulmonary Doppler Signals in Patients With Systemic Sclerosis(SSc) (NCT02278445) | Echosense Ltd. | 2014-11-01 |
| Vocal Intervention in Systemic Sclerosis (NCT02821663) | Medical University of Vienna | 2014-11-01 |
| Evaluating Lung Doppler Signals in Patients With Systemic Sclerosis (SSc) (NCT02246348) | Echosense Ltd. | 2014-09-01 |
| Detecting Pulmonary Arterial Hypertension (PAH) in Patients With Systemic Sclerosis (SSc) by Ultrasound (NCT02243111) | Echosense Ltd. | 2014-09-01 |
| Early Treatment of Borderline Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (SSc-APAH) (NCT02290613) | Heidelberg University | 2014-07-01 |
| EFFECTS OF THE MICRO REINJECTION OF AUTOLOGOUS ADIPOSE TISSUE IN THE FACE OF PATIENTS WITH SYSTEMIC SCLEROSIS (NCT02206672) | Assistance Publique Hopitaux De Marseille | 2014-07-01 |
| Divalproex Sodium in the Treatment of the Cutaneous Manifestations of Scleroderma (NCT02166229) | Yale University | 2014-06-01 |
| Soluble VE-cadherin and VE-cadherin Antibody in Sclerodermic Sclerosis (NCT02212249) | University Hospital, Grenoble | 2014-05-01 |
| Swallowing Difficulties With Medication Intake and Coping Strategies in Patients With Systemic Sclerosis (NCT02105818) | Kurt Hersberger | 2014-03-01 |
| The Role of Gastroesophageal Reflux in Scleroderma Pulmonary Fibrosis (NCT02136394) | Royal Brompton & Harefield NHS Foundation Trust | 2014-02-01 |
| Induction of Regulatory t Cells by Low Dose il2 in Autoimmune and Inflammatory Diseases (NCT01988506) | Assistance Publique - Hôpitaux de Paris | 2014-01-06 |
| Lysyl Oxidase, Semaphorin 7a and Semaphorin 3a in Patients With Systemic Sclerosis (NCT01943968) | Hillel Yaffe Medical Center | 2013-12-01 |
| Safety and Tolerability of Pirfenidone in Participants With Systemic Sclerosis-Related Interstitial Lung Disease (SSc-ILD) (LOTUSS) (NCT01933334) | Genentech, Inc. | 2013-10-01 |
| Gastroesophageal Reflux Treatment in Scleroderma (NCT01878526) | Khon Kaen University | 2013-06-01 |
| Prevalence and Predictors of Proton Pump Inhibitor Partial Response in Gastroesophageal Reflux Disease in Systemic Sclerosis (NCT03561233) | Khon Kaen University | 2013-05-01 |
| Treatment and Prevention of Progression of Interstitial Lung Disease in Systemic Sclerosis (NCT01858259) | Gabriela Riemekasten | 2013-05-01 |
| Clinical Trial of Probiotics in Systemic Sclerosis Associated Gastrointestinal Disease (NCT01804959) | Singapore General Hospital | 2013-05-01 |
| Rituximab in Systemic Sclerosis (NCT01748084) | Assistance Publique - Hôpitaux de Paris | 2013-04-09 |
| Prevention and Treatment of Digital Ulcers in Systemic Sclerosis (NCT01836263) | marco matucci cerinic | 2013-04-01 |
| Development and Prevention of Severe Heart Disease in Systemic Sclerosis (NCT01829126) | Gabriele Valentini | 2013-04-01 |
| Improvement of Hand Dysfunction by Arthritis in Systemic Sclerosis (NCT01834157) | Prof. Laszlo Czirjak | 2013-04-01 |
| Development and Prevention of Pulmonary Hypertension in Systemic Sclerosis (NCT01840748) | University of Paris 5 - Rene Descartes | 2013-04-01 |
| IVIG Treatment in Systemic Sclerosis (NCT01785056) | Georgetown University | 2013-04-01 |
| Cyclophosphamide Systemic Sclerosis Associated Interstitial Lung Disease (NCT01570764) | Assistance Publique - Hôpitaux de Paris | 2013-01-14 |
| Proof of Biological Activity of SAR100842 in Systemic Sclerosis (NCT01651143) | Sanofi | 2013-01-01 |
| Assessment of the Subcutaneous Reinjection of Human Autologous Adipose-derived Stromal Vascular Fraction (Celution® System) in the Hands of Patients Suffering From Systemic Sclerosis (NCT01813279) | Assistance Publique Hopitaux De Marseille | 2012-11-01 |
| Conception of an ICF Core Set for Systemic Sclerosis (NCT01848418) | Assistance Publique - Hôpitaux de Paris | 2012-10-27 |
| Study of Pomalidomide (CC-4047) to Evaluate Safety, Tolerability, Pharmacokinetics, Pharmacodynamics and Effectiveness for Patients With Systemic Sclerosis With Interstitial Lung Disease (NCT01559129) | Celgene | 2012-08-09 |
| Belimumab for the Treatment of Diffuse Cutaneous Systemic Sclerosis (NCT01670565) | Hospital for Special Surgery, New York | 2012-08-01 |
| Vasculopathy, Inflammation and Systemic Sclerosis (NCT02562079) | University Hospital, Bordeaux | 2012-03-01 |
| Sacroiliitis in Systemic Sclerosis (NCT01673633) | Cukurova University | 2012-01-01 |
| Macitentan for the Treatment of Digital Ulcers in Systemic Sclerosis Patients (NCT01474109) | Actelion | 2011-12-01 |
| IL1-TRAP, Rilonacept, in Systemic Sclerosis (NCT01538719) | Boston University | 2011-12-01 |
| An Open-Label Study to Evaluate Biomarkers and Safety in Systemic Sclerosis Patients Treated With ABR-215757 (Paquinimod) (NCT01487551) | Active Biotech AB | 2011-12-01 |
| Hemodynamic Changes in Connective Tissue Disease (NCT01468792) | Medical University of Graz | 2011-09-01 |
| Bosentan in Systemic Sclerosis (NCT01395732) | Actelion | 2011-03-31 |
| Neuropsychiatric Scleroderma Study: Systematic Evaluation of Neuropsychiatric Involvement in Systemic Sclerosis (NCT01488214) | University Hospital, Lille | 2011-02-16 |
| Sonographic and Laboratory Evaluation of the Thyroid Gland in Patients With Systemic Sclerosis (NCT01270425) | Meir Medical Center | 2011-01-01 |
| Digital Ulceration (NCT01377090) | Actelion | 2011-01-01 |
| Nilotinib in the Treatment of Systemic Sclerosis (NCT01166139) | Hospital for Special Surgery, New York | 2010-07-01 |
| Auto-immunity and Pulmonary Arterial Hypertension (NCT01208792) | Assistance Publique - Hôpitaux de Paris | 2010-06-15 |
| A Clinical Trial of Ambrisentan and Tadalafil in Pulmonary Arterial Hypertension Associated With Systemic Sclerosis (NCT01042158) | Johns Hopkins University | 2010-01-01 |
| Effects of Intensive Aerobic and Muscle Endurance Exercise in Patients With Systemic Sclerosis - a Pilot Study (NCT01813578) | Karolinska University Hospital | 2009-10-01 |
| Open-Label Study of Oral Treprostinil in Digital Ulcers (NCT00848107) | United Therapeutics | 2009-09-01 |
| The CARRA Registry (NCT01697254) | Duke University | 2009-08-01 |
| Allogeneic Mesenchymal Stem Cells Transplantation for Systemic Sclerosis (SSc) (NCT00962923) | The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School | 2009-08-01 |
| Small Intestinal Mucosal Abnormalities in Systemic Sclerosis Using Capsule Endoscopy (NCT00958672) | University Hospital, Rouen | 2009-08-01 |
| Digital Ischemic Lesions in Scleroderma Treated With Oral Treprostinil Diethanolamine (NCT00775463) | United Therapeutics | 2009-05-01 |
| Exercise Induced Pulmonary Hypertension in Systemic Sclerosis and Treatment With Ambrisentan (NCT01051960) | University of California, Los Angeles | 2009-03-01 |
| Low-Dose Oral Imatinib for Scleroderma Pulmonary Involvement (NCT00573326) | Azienda Ospedaliera Universitaria Policlinico | 2009-02-01 |
| Pharmacokinetics of Oral Treprostinil in Patients With Systemic Sclerosis (NCT00848939) | United Therapeutics | 2008-12-01 |
| AIMSPRO in Established Diffuse Cutaneous Systemic Sclerosis (NCT00769028) | Daval International Limited | 2008-12-01 |
| Skin Biopsy Specimens as Biomarkers of Systemic Sclerosis and Response to Mycophenolate Mofetil (NCT00853788) | Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD) | 2008-11-01 |
| Early, Simple and Reliable Detection of Pulmonary Arterial Hypertension (PAH) in Systemic Sclerosis (SSc) (NCT00706082) | Actelion | 2008-10-01 |
| Stimulatory Autoantibodies to the Platelet-Derived Growth Factor Receptor (PDGFR) in Patients With Systemic Sclerosis (NCT00667134) | University of Michigan | 2008-03-01 |
| Effectiveness of UVA1-irradiation in the Treatment of Early Skin Fibrosis in Patients Suffering From Systemic Sclerosis (NCT00628797) | Nicolas Hunzelmann | 2008-02-01 |
| Early Therapy of Pulmonary Arterial Hypertension (NCT00909337) | Medical University of Graz | 2008-01-01 |
| Pulmonary Arterial Hypertension in Systemic Sclerosis (NCT00617487) | Fondazione IRCCS Policlinico San Matteo di Pavia | 2007-12-01 |
| Investigation of Coronary and Pulmonary Circulatory Parameters in Systemic Sclerosis (NCT00843102) | University of Pecs | 2007-12-01 |
| Oral Health and People With Systemic Sclerosis (NCT01817361) | University of Alabama at Birmingham | 2007-10-01 |
| Imatinib Mesylate (Gleevec) in the Treatment of Systemic Sclerosis (NCT00555581) | Hospital for Special Surgery, New York | 2007-08-01 |
| Reduced Intensity Transplant in Medically Refractory Systemic Lupus Erythematosus (SLE) and Systemic Sclerosis (SSc) (NCT00684255) | New York Medical College | 2007-08-01 |
| A Study Using The Experimental Drug Called Imatinib (Gleevec) in Subjects With Systemic Sclerosis (NCT00512902) | University of California, Los Angeles | 2007-08-01 |
| Non-Invasive Diagnostic and Functional Evaluation of Cardiac Involvement in Patients With Systemic Sclerosis (NCT00453752) | Medical University of Warsaw | 2006-04-01 |
| The Effect of Physical Therapy on Raynaud's Phenomenon Secondary to Systemic Sclerosis (NCT00946738) | Charite University, Berlin, Germany | 2004-10-01 |
| Efficacy and Safety of Oral Bosentan on Healing/Prevention of Digital (Finger) Ulcers in Patients With Scleroderma (NCT00077584) | Actelion | 2003-10-01 |
| Nonmyeloablative Allo Stem Cell Transplant for Severe Autoimmune Diseases (NCT00849745) | Duke University | 2003-01-01 |
| Rapamycin vs Methotrexate in Diffuse SSc (NCT00241189) | University of California, Los Angeles | 2002-08-01 |
| Safety and Value of Self Bone Marrow Transplants Following Chemotherapy in Scleroderma Patients (NCT00040651) | National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | 2002-07-01 |
| Small Bowel Motor Impairment in Scleroderma: Results of a Prospective 5-year Manometric Follow-up (NCT00213460) | University Hospital, Rouen | 2001-08-01 |
| Trial of IC351 in Female Scleroderma Patients With Raynaud's and Sexual Dysfunction (NCT00707187) | University of Medicine and Dentistry of New Jersey | 2001-07-01 |
| Psychological Treatments for Scleroderma (NCT00007267) | Johns Hopkins University | 2001-06-01 |
| Pilot Study of Total Body Irradiation in Combination With Cyclophosphamide, Anti-thymocyte Globulin, and Autologous CD34-Selected Peripheral Blood Stem Cell Transplantation in Children With Refractory Autoimmune Disorders (NCT00010335) | Fred Hutchinson Cancer Center | 2000-11-01 |
| Phase II Pilot Study of Cyclophosphamide and Rabbit Anti-Thymocyte Globulin as Salvage Therapy in Patients With Diffuse Systemic Sclerosis (NCT00016458) | Fred Hutchinson Cancer Center | 2000-06-01 |
| Stem Cell Transplant to Treat Patients With Systemic Sclerosis (NCT00058578) | Baylor College of Medicine | 1999-06-01 |
| Genetic Study of the FBN1 Gene and Fibrillin-1 Abnormalities in Choctaw Native Americans and Other Patients With Systemic Sclerosis (NCT00006393) | National Center for Research Resources (NCRR) | 1998-07-01 |
| Effect of Different Iloprost Doses on Symptoms in Systemic Sclerosis (NCT00622687) | Charite University, Berlin, Germany | 1997-09-01 |
| Phase III Randomized, Double-Blind, Placebo-Controlled Study of Oral Iloprost for Raynaud's Phenomenon Secondary to Systemic Sclerosis (NCT00004786) | National Center for Research Resources (NCRR) | 1995-12-01 |
| Spontaneous Coronary Artery Dissection (SCAD) and Autoimmunity (NCT03941184) | Mayo Clinic | 1995-01-01 |
| Phase II Study of Recombinant Relaxin for Progressive Systemic Sclerosis (NCT00004380) | National Center for Research Resources (NCRR) | 1991-12-01 |
| Safety, Tolerability, and Pharmacokinetics of CAT-192 (Human Anti-TGF-Beta1 Monoclonal Antibody) in Patients With Early Stage Diffuse Systemic Sclerosis (NCT00043706) | Genzyme, a Sanofi Company | |