| De-escalation of Empirical Antimicrobial Therapy Study in Severe Sepsis (NCT01626612) | Assistance Publique Hopitaux De Marseille | 2012-02-01 |
| Simplified Severe Sepsis Protocol in Zambia (NCT01449916) | Vanderbilt University | 2012-02-01 |
| Muscle Atrophy in Patients With Severe Sepsis (NCT01717651) | Ohio State University | 2011-12-01 |
| A Prospective Study of The Complement Depletion in Patients With Severe Abdominal Sepsis (NCT01568853) | Jinling Hospital, China | 2011-11-01 |
| Peripheral Perfusion Targeted Fluid Management (NCT01397474) | Erasmus Medical Center | 2011-10-01 |
| Pharmacokinetic and Biomarker Study of Pioglitazone in Adolescents With Severe Sepsis and Septic Shock (NCT01352182) | Children's Hospital Medical Center, Cincinnati | 2011-10-01 |
| Preemptive Resuscitation for Eradication of Septic Shock (NCT01449721) | Christiana Care Health Services | 2011-09-01 |
| Safety and Efficacy of Talactoferrin Alfa in Patients With Severe Sepsis (NCT01273779) | Agennix | 2011-06-01 |
| Lotta Alla Sepsi Ospedaliera - Fighting Hospital Sepsis (NCT01804764) | University of Milano Bicocca | 2011-05-01 |
| S.A.F.E.BT System Extracorporeal Treatment With DIAPACT CRRT (NCT01312675) | B. Braun Medical Inc. | 2011-04-01 |
| The Effect of Three Different Fluids(Albumin 5%, Normal Saline, Hydroxyethyl Starch 130 kD) on Microcirculation in Severe Sepsis/Septic Shock Patients (NCT01319630) | Mercy Research | 2011-04-01 |
| The Effect of Ketanserin on the Microcirculation in Sepsis (NCT01329887) | Frisius Medisch Centrum | 2011-03-01 |
| Glutamine Supplementation in Critically Ill Patients With Severe Sepsis (NCT03048994) | Changi General Hospital | 2011-01-01 |
| Early Warning System for Clinical Deterioration on General Hospital Wards (NCT01280942) | Washington University School of Medicine | 2011-01-01 |
| SIRS and Bacterial Sepsis Discrimination by Biomarkers in ICU (NCT01378169) | Fondation Hôpital Saint-Joseph | 2011-01-01 |
| Efficacy of Hydrocortisone in Treatment of Severe Sepsis/Septic Shock Patients With Acute Lung Injury/Acute Respiratory Distress Syndrome (ARDS) (NCT01284452) | Mahidol University | 2010-12-01 |
| A Study to Compare the Efficacy and Safety of 2 Dosing Regimens of IV Infusions of AZD9773 (CytoFab™) With Placebo in Adult Patients With Severe Sepsis and/or Septic Shock (NCT01145560) | AstraZeneca | 2010-10-01 |
| Epidemiology of Septic Shock in Medical or Polyvalent ICU in the North-East Region of France (NCT01903746) | Centre Hospitalier Universitaire Dijon | 2010-10-01 |
| Zinc Therapy in Critical Illness (NCT01162109) | University of Vermont | 2010-09-01 |
| 4G/5G Polymorphism of Plasminogen Activator Inhibitor-1 Gene and Disseminated Intravascular Coagulation in Severe Sepsis and Septic Shock (NCT01211899) | Hallym University Medical Center | 2010-09-01 |
| Sepsis Metabolomics (NCT01649440) | Chinese PLA General Hospital | 2010-07-01 |
| Efficacy of Bevacizumab in Preventing Acute Respiratory Distress Syndrome (ARDS) (NCT01314066) | Weill Medical College of Cornell University | 2010-07-01 |
| Serum Proteomics Analysis for Sepsis (NCT01493466) | Chinese PLA General Hospital | 2010-05-01 |
| Impact of Early Goal-directed Fluid Therapy in Septic Patients Undergoing Emergency Surgery (NCT01654003) | University Hospital, Geneva | 2010-04-01 |
| Microcirculatory Changes During Magnesium Sulphate Infusion in Sepsis (NCT01332734) | Frisius Medisch Centrum | 2010-03-01 |
| The Effect of Esmolol on Clinical Prognosis of Patients With Severe Sepsis (NCT02794025) | Fujian Provincial Hospital | 2010-01-01 |
| Scandinavian Starch for Severe Sepsis/Septic Shock Trial (NCT00962156) | Anders Perner | 2009-12-01 |
| Placebo Controlled Trial of Sodium Selenite and Procalcitonin Guided Antimicrobial Therapy in Severe Sepsis (NCT00832039) | Kompetenznetz Sepsis | 2009-11-01 |
| Safety and Efficacy of Procalcitonin Guided Antibiotic Therapy in Adult Intensive Care Units (ICU's) (NCT01139489) | Amsterdam UMC, location VUmc | 2009-11-01 |
| GCIV as an Adjuvant Therapy for Community-Acquired Severe Sepsis or Septic Shock (NCT01315496) | Green Cross Corporation | 2009-10-01 |
| Use of Inflammatory Biomarkers to Guide Antibiotic Therapy in Patients With Severe Infections (NCT00934011) | Federal University of Minas Gerais | 2009-09-01 |
| Activated Protein C and Microcirculation (NCT01806428) | Università Politecnica delle Marche | 2009-07-01 |
| Comparison of Total, Salivary and Calculated Free Cortisol Levels in Patients With Severe Sepsis (NCT02589431) | TC Erciyes University | 2009-06-01 |
| Fluid Resuscitation in Early Septic Shock (NCT00819416) | Ottawa Hospital Research Institute | 2009-02-01 |
| Influence of Acute Respiratory Distress Syndrome (ARDS) and Severe Sepsis on sRAGE Levels in ICU Patients (NCT00811629) | University Hospital, Clermont-Ferrand | 2009-01-01 |
| Hydrocortisone for Prevention of Septic Shock (NCT00670254) | Charite University, Berlin, Germany | 2009-01-01 |
| Pro-inflammatory Cytokines Profile and Mortality Rate of Critically Ill Septic Patients Following Plasmapheresis (NCT01249222) | Tehran University of Medical Sciences | 2008-11-01 |
| Evaluation of MorphoTEP With the FDG Among Patients in Severe Sepsis of Unspecified Etiology (NCT00791310) | Central Hospital, Nancy, France | 2008-11-01 |
| Echocardiography in Septic Shock (NCT02135796) | Intermountain Health Care, Inc. | 2008-10-01 |
| Autonomic Nervous System Alteration Induce by Sepsis: Assessment and Prognosis Impact (NCT00835913) | University Hospital, Grenoble | 2008-10-01 |
| Australasian Resuscitation In Sepsis Evaluation Randomised Controlled Trial (NCT00975793) | Belinda Howe | 2008-10-01 |
| Septic Encephalopathy and Late Cognitive Dysfunction (NCT00772096) | University Hospital, Basel, Switzerland | 2008-10-01 |
| Volume Replacement With Albumin in Severe Sepsis (NCT00707122) | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 2008-07-01 |
| Efficacy of Thymosin alpha1 for Severe Sepsis (NCT00711620) | Sun Yat-sen University | 2008-05-01 |
| Safety and Efficacy Study of Recombinant Human Lactoferrin to Treat Severe Sepsis (NCT00630656) | Agennix | 2008-04-01 |
| Protocolized Care for Early Septic Shock (NCT00510835) | University of Pittsburgh | 2008-03-01 |
| Clinical Assessment of Fish Oil-based Lipid Emulsion Infusions in Critical Patients With Severe Sepsis (NCT00634075) | Li Shin Hospital | 2008-03-01 |
| Endothelium in Severe Sepsis (NCT00793442) | Beth Israel Deaconess Medical Center | 2008-03-01 |
| Study of Procalcitonin (PCT)-Guided Antibiotic Use in Severe Sepsis Patients Without Obvious Infection (NCT01025180) | Brahms France | 2007-12-01 |
| Sepsis Institutional Registry in Hospital Italiano de Buenos Aires (NCT01403935) | Hospital Italiano de Buenos Aires | 2007-12-01 |
| Skeletal Muscle and Platelet Mitochondrial Dysfunction During Sepsis (NCT00541827) | Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico | 2007-10-01 |
| Comparison of Two Antibiotic Regimen (Meropenem Versus Meropenem+Moxifloxacin)in the Treatment of Severe Sepsis and Septic Shock (NCT00534287) | Kompetenznetz Sepsis | 2007-10-01 |
| Clarithromycin as Immunomodulator for the Management of Sepsis (NCT01223690) | University of Athens | 2007-07-01 |
| Minimally-Invasive Cardiovascular Hemodynamic Optimization (MiCHO) Versus Early Goal-Directed Therapy (EGDT) in the Management of Septic Shock (NCT00535821) | Loma Linda University | 2007-06-01 |
| Microcirculation Guided Therapy Versus "Standard Treatment" of Severe Sepsis (NCT00484133) | Onze Lieve Vrouwe Gasthuis | 2007-06-01 |
| The Effects of Eicosapentaenoic Acid (EPA), Gamma-Linolenic Acid (GLA) and Antioxidants in the Treatment of Sepsis (NCT00329680) | Fernandes Tavora Hospital | 2007-06-01 |
| The Utility of Ischemia Modified Albumin (IMA) in Sepsis (NCT00448968) | Inverness Medical Innovations | 2007-03-01 |
| Effect of Docosahexaenoic Acid on the Inflammatory Response and Clinical Outcomes From Surgical Patients (NCT01049529) | Coordinación de Investigación en Salud, Mexico | 2007-03-01 |
| Clinical Trial of the Optimal Endpoint of Early Sepsis Resuscitation (NCT00372502) | National Institute of General Medical Sciences (NIGMS) | 2007-01-01 |
| Evaluate Protein C Levels in Severe Sepsis Patients on Drotrecogin Alfa (Activated) (NCT00386425) | Eli Lilly and Company | 2006-11-01 |
| Protocol-driven Hemodynamic Support for Patients With Septic Shock (NCT00335907) | National Institute of General Medical Sciences (NIGMS) | 2006-09-01 |
| Pharmacokinetic of Ceftriaxone in Septic ICU Patients (NCT00449800) | Association Pour La Promotion A Tours De La Reanimation Medicale | 2006-07-01 |
| ACCESS: A Controlled Comparison of Eritoran Tetrasodium and Placebo in Patients With Severe Sepsis (NCT00334828) | Eisai Inc. | 2006-06-01 |
| Alterations of Immunologic Mediators During Severe Sepsis (NCT00484146) | Klinikum St. Georg gGmbH | 2006-06-01 |
| Investigation of Correlation Between Interstitial and Arterial Blood Glucose Concentrations in Septic Patients (NCT00463645) | Medical University of Graz | 2005-09-01 |
| Near Infrared Spectroscopy (NIRS) in Severe Sepsis (NCT00167596) | University of Versailles | 2005-07-01 |
| BaSES Trial: Basel Starch Evaluation in Sepsis (NCT00273728) | University Hospital, Basel, Switzerland | 2005-05-01 |
| Effect of Hyperglycemia in PAI-1 Activity and the Relationship With Outcome in Severe Sepsis and Septic Shock (NCT00159952) | Policlinico Hospital | 2004-11-01 |
| Comparison of Pediatric Septic Shock Treatment With and Without Central Venous Oxygen Saturation Monitoring (NCT00407823) | University of Sao Paulo | 2004-01-01 |
| Efficacy of Volume Substitution and Insulin Therapy in Severe Sepsis (VISEP Trial) (NCT00135473) | SepNet - Critical Care Trials Group | 2003-04-01 |
| Comparative Study of the Protein C Pathway in Septic and Non Septic Patients With Organ Failure (NCT00361725) | Assistance Publique - Hôpitaux de Paris | 2003-03-01 |
| An Open Label Study of Severe Sepsis in Adults (NCT00568893) | Eli Lilly and Company | 2003-01-01 |
| Selenium, as Sodium Selenite, in the Treatment of Septic Shock (NCT00207844) | Centre Hospitalier de Meaux | 2002-01-01 |
| Norepinephrine Plus Dobutamine Versus Epinephrine Alone for the Management of Septic Shock (NCT00148278) | University of Versailles | 1999-10-01 |
| A Non-invasive Approach to the Assessment of Volume Status in Mechanically Ventilated Septic Patients. (NCT00398736) | Charite University, Berlin, Germany | |
| Extravascular Lung Water Index in Severe Sepsis (NCT00986271) | Chang Gung Memorial Hospital | |