| OPsumit USers Registry (NCT02126943) | Actelion | 2014-04-30 |
| Clinical Trial to Evaluate the Long-term Safety of Udenafil in Patient With PAH (NCT02304198) | Dong-A ST Co., Ltd. | 2014-04-01 |
| Sleep Disordered Breathing in Precapillary Pulmonary Hypertension: Effect of CPAP Treatment (NCT02583906) | Universitaire Ziekenhuizen KU Leuven | 2014-04-01 |
| Comparative PK PD Study in PAH Patients (Fox vs. I-Neb) (NCT02032836) | Bayer | 2014-03-10 |
| A Pulmonary Arterial Hypertension Study With Macitentan to Validate the PAH-SYMPACT™ in France, Italy and Spain (NCT02081690) | Actelion | 2014-03-01 |
| National Cohort Study of Idiopathic and Heritable Pulmonary Arterial Hypertension (NCT01907295) | University of Cambridge | 2014-02-01 |
| Feasibility of Slow-paced Respiration Therapy for Treatment of a Symptom Cluster in Pulmonary Arterial Hypertension (NCT02080533) | University of Pennsylvania | 2014-02-01 |
| Spironolactone for Pulmonary Arterial Hypertension (NCT01712620) | National Institutes of Health Clinical Center (CC) | 2014-01-10 |
| Testing of HIV Protease Inhibitors to Suppress Inflammation and Improve Cardio Pulmonary Hemodynamics in Subjects With Pulmonary Arterial Hypertension (NCT02023450) | The Third Xiangya Hospital of Central South University | 2013-12-01 |
| Acute Dosing of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-003) (NCT01934647) | Merck Sharp & Dohme LLC | 2013-11-22 |
| Study to Assess the Safety, Tolerability and Pharmacokinetics (PK) of MK-8892 in Participants With Pulmonary Arterial Hypertension (PAH) (MK-8892-005) (NCT01926509) | Merck Sharp & Dohme LLC | 2013-11-14 |
| LenusPro Pump in PAH Treated With Treprostinil (NCT02889315) | Department of Pulmonary Circulation and Thromboembolic Diseases, Medical Center for Postgraduate Med | 2013-11-01 |
| Compassionate Use of Beraprost Sodium 314d Modified Release for Patients With Pulmonary Arterial Hypertension (PAH) (NCT01966302) | Lundquist Institute for Biomedical Innovation at Harbor-UCLA Medical Center | 2013-11-01 |
| BEET PAH: a Study to Assess the Effects of Beetroot Juice in Patients With Pulmonary Arterial Hypertension (NCT02000856) | Uppsala University | 2013-11-01 |
| Fluoxetine in Pulmonary Arterial Hypertension (PAH) Trial (NCT03638908) | University of Texas Southwestern Medical Center | 2013-11-01 |
| Bosentan In Exercise Induced Pulmonary Arterial Hypertension in CongenitaL Heart diseasE (NCT01827059) | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | 2013-10-01 |
| Pharmacokinetic Study of Sub-q and IV Treprostinil in Kids With Pulmonary Arterial Hypertension (PAH) (NCT02318186) | Jeffrey A. Feinstein | 2013-10-01 |
| Transforming Growth Factor Beta Signalling in the Development of Muscle Weakness in Pulmonary Arterial Hypertension (NCT01847716) | Imperial College London | 2013-10-01 |
| Novel Screening Strategies for Scleroderma PAH (NCT01959815) | University of Michigan | 2013-09-26 |
| Observational Description of Compliance for the Daily Ventavis Use Via the Insight Program in Class III Pulmonary Arterial Hypertension Patients (NCT01781052) | Bayer | 2013-09-11 |
| An Open-Label, Long-Term Study of Oral Treprostinil in Subjects With Pulmonary Arterial Hypertension (NCT01560637) | United Therapeutics | 2013-09-11 |
| Clinical Study to Assess the Long-term Safety, Tolerability, and Efficacy of Macitentan in Subjects With Eisenmenger Syndrome (NCT01739400) | Actelion | 2013-09-10 |
| A Pharmacokinetic Substudy of the TDE-PH-304 Protocol (NCT01934582) | United Therapeutics | 2013-08-01 |
| Resynchronisation Therapy of Right Ventricle in Pulmonary Arterial Hypertension (NCT01905189) | University Hospital, Caen | 2013-07-01 |
| (-)-Epicatechin and Pulmonary Arterial Hypertension (NCT01880866) | University of California, San Francisco | 2013-07-01 |
| Patient Reported Outcomes in Pulmonary Arterial Hypertension (NCT01792622) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2013-07-01 |
| Beraprost-314d Added-on to Tyvaso® (BEAT) (NCT01908699) | Lung Biotechnology PBC | 2013-05-31 |
| Clinical Study to Evaluate the Effects of Macitentan on Exercise Capacity in Subjects With Eisenmenger Syndrome (NCT01743001) | Actelion | 2013-05-21 |
| Efficacy and Safety Study of Sodium Tanshinone IIA Sulfonate on Pulmonary Hypertension (NCT01637675) | The First Affiliated Hospital of Guangzhou Medical University | 2013-05-01 |
| To Compare the Pharmacokinetics of Traclear 62.5 mg Tablets and HGP1206 125mg 1 Tablet in Healthy Male Volunteers (NCT01864863) | Hanmi Pharmaceutical Company Limited | 2013-04-01 |
| Safety Study of PLX-PAD Cells to Treat Pulmonary Arterial Hypertension (PAH) (NCT01795950) | United Therapeutics | 2013-04-01 |
| Obstructive Sleep Apnea (OSA) in Pulmonary Arterial Hypertension (PAH) (NCT01835080) | Inova Health Care Services | 2013-04-01 |
| Clinical Study of Macitentan in Patients With Pulmonary Arterial Hypertension to Psychometrically Validate the PAH-SYMPACT Instrument (NCT01841762) | Actelion | 2013-04-01 |
| A Rising Single Dose Study of the Safety, Tolerability, Pharmacokinetics (PK) and Pharmacodynamics of MK-8892 (MK-8892-001) (NCT01798849) | Merck Sharp & Dohme LLC | 2013-03-15 |
| Non-invasive Diagnostics of Pulmonary Hypertension With Dual Energy Computed Tomography (NCT01829672) | Medical University of Graz | 2013-03-01 |
| Long-term Study of AIR001 in Subjects With WHO Group 1 Pulmonary Arterial Hypertension Who Completed AIR001-CS05 (NCT01725269) | Aires Pharmaceuticals, Inc. | 2013-03-01 |
| MIF- Thyroxine Interactions in the Pathogenesis of Pulmonary Arterial Hypertension (NCT02858791) | Northwell Health | 2013-02-01 |
| Iron Status and Hypoxic Pulmonary Vascular Responses (NCT01847352) | University of Oxford | 2013-02-01 |
| HYPID (Pulmonary Hypertension in Interstitial Lung Disease) EXTENSION (NCT02799771) | Groupe d'Etudes et de Recherche sur les Maladies Orphelines Pulmonaires | 2013-02-01 |
| Evaluation of Pulmonary Perfusion Heterogeneity and Compliance in Patients With Pulmonary Hypertension Using Positron Emission Tomography Imaging (NCT01461343) | Massachusetts General Hospital | 2013-02-01 |
| Tyvaso Dosing and Titration Evaluation: TyTRATE Registry (NCT01799473) | United Therapeutics | 2013-01-01 |
| The Risk of Adverse Pregnancy Outcomes for Long-term Exposure to Air Pollution in Pregnant Patients With Pulmonary Hypertension (NCT07164157) | Wei Huang | 2013-01-01 |
| Study Of Right Ventricular Performance In PAH Patients Treated With Rapid Dose Treprostinil (Remodulin) (NCT02074449) | University of Arizona | 2012-12-01 |
| A Phase 2 Study to Determine the Safety and Efficacy of AIR001 in Subjects With Pulmonary Arterial Hypertension (PAH) (NCT01725256) | Aires Pharmaceuticals, Inc. | 2012-11-01 |
| Anastrozole in Patients With Pulmonary Arterial Hypertension (NCT01545336) | University of Pennsylvania | 2012-10-01 |
| Study of the Initial Combination of Bosentan With Iloprost in the Treatment of Pulmonary Hypertension Patients (NCT01712997) | Air Force Military Medical University, China | 2012-09-01 |
| Beta Blockers for Treatment of Pulmonary Arterial Hypertension in Children (NCT01723371) | The Hospital for Sick Children | 2012-09-01 |
| Vardenafil as add-on Therapy for Patients With Pulmonary Hypertension Treated With Inhaled Iloprost (NCT01649739) | Rabin Medical Center | 2012-09-01 |
| Safety And Efficacy Of Sildenafil In Children With Pulmonary Arterial Hypertension (NCT01642407) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2012-08-24 |
| A Pharmacokinetics Study for Pediatric Participants With Pulmonary Arterial Hypertension (NCT01484431) | Eli Lilly and Company | 2012-07-17 |
| Efficacy Study of Cardizem in Pulmonary Arterial Hypertension (NCT01645826) | University of South Florida | 2012-07-01 |
| FK506 (Tacrolimus) in Pulmonary Arterial Hypertension (NCT01647945) | Edda Spiekerkoetter | 2012-07-01 |
| Eisenmenger Quality Enhancement Research Initiative (NCT01623492) | Actelion | 2012-07-01 |
| Hypotonic Treprostinil Subcutaneous Infusion for Control of Treprostinil Related Site Pain (NCT01615627) | Jewish General Hospital | 2012-07-01 |
| Phase III Clinical Worsening Study of UT-15C in Subjects With PAH Receiving Background Oral Monotherapy (NCT01560624) | United Therapeutics | 2012-06-26 |
| Inhaled Treprostinil for PAH: Open-label Extension (NCT01557660) | United Therapeutics | 2012-06-01 |
| Safety and Efficacy of Inhaled Treprostinil in Patients With PAH (NCT01557647) | United Therapeutics | 2012-06-01 |
| Combined Use of Angiography, Optical Coherence Tomography and Intravascular Ultrasound in Evaluation of Pulmonary Vascular Structure and Function in Patients With Pulmonary Arterial Hypertension Treated With Oral Bosentan (NCT01508780) | Massachusetts General Hospital | 2012-05-01 |
| Assessmet of Patients With PAH Right Ventricular Volume (NCT01557582) | VentriPoint Diagnostics Ltd. | 2012-04-01 |
| Remodulin® to Oral Treprostinil Transition (NCT01588405) | United Therapeutics | 2012-04-01 |
| Safety and Tolerability of Rapid Dose Titration of Subcutaneous Remodulin® Therapy in PAH Subjects (RAPID) (NCT02847260) | United Therapeutics | 2012-04-01 |
| Screening of Pulmonary Arterial Hypertension in BMPR2 Mutation Carriers (NCT01600898) | Assistance Publique - Hôpitaux de Paris | 2012-03-01 |
| Surgical Valvuloplasty for Congenital Mitral Insufficiency (NCT03567668) | Hong Liu | 2012-01-01 |
| Oral Iron Supplementation in Pulmonary Hypertension (NCT01446848) | The Cleveland Clinic | 2012-01-01 |
| Effects of Apelin on the Lung Circulation in Pulmonary Hypertension (NCT01457170) | Golden Jubilee National Hospital | 2012-01-01 |
| Prevalence of Pulmonary Hypertension (PAH) in Patients With Thalassemia (NCT01496963) | Ente Ospedaliero Ospedali Galliera | 2012-01-01 |
| Respiratory and Physical Therapy in Patients With Associated Pulmonary Arterial Hypertension (APAH) With Congenital Heart Defects (NCT01397110) | Heidelberg University | 2012-01-01 |
| Lidocaine Subcutaneous Infusion for Control of Treprostinil Related Site Pain (NCT01433328) | Jewish General Hospital | 2012-01-01 |
| Adult Congenital Heart Disease Registry (QuERI) (NCT01659411) | Actelion | 2011-12-01 |
| Impact of Inhaled Treprostinil Sodium on Ventilation Perfusion Matching (NCT01494896) | University of Florida | 2011-11-01 |
| Pharmacokinetics of Understudied Drugs Administered to Children Per Standard of Care (NCT01431326) | Daniel Benjamin | 2011-11-01 |
| A Multinational, Multicenter, Study to Assess the Efficacy and Safety of BPS-314d-MR in Subjects With Pulmonary Arterial Hypertension Currently Receiving Treatment With an Endothelin Receptor Antagonist and/or a Phosphodiesterase-5 Inhibitor (NCT01458236) | Lung Biotechnology PBC | 2011-11-01 |
| Educational Training Influence in Patients With PAH(Pulmonary Artery Hypertension) on Inhaled Ventavis Treatment Adherence Evaluated Trough INSIGHT System (NCT01468545) | Bayer | 2011-10-01 |
| Addition of UT-15C SR to Pulmonary Arterial Hypertension Patients Currently Receiving Tyvaso® (NCT01477333) | United Therapeutics | 2011-10-01 |
| Drug Therapy and Surgery in Congenital Heart Disease With Pulmonary Hypertension (NCT01548950) | University of Sao Paulo General Hospital | 2011-09-01 |
| A Study of Ranolazine Acute Administration and Short Term Administration in Pulmonary Arterial Hypertension (NCT01757808) | University of Chicago | 2011-08-01 |
| Early Detection of Pulmonary Arterial Hypertension Using Cardiac Magnetic Resonance Imaging (NCT01451255) | Mayo Clinic | 2011-08-01 |
| Efficacy and Safety Study of Udenafil in Patient With Pulmonary Arterial Hypertension(PAH) (NCT01553721) | Dong-A ST Co., Ltd. | 2011-08-01 |
| Measuring Blood Pressure in the Lung Circulation With Sonar Technology (Echo-Doppler) (NCT01357746) | Echosense Ltd. | 2011-07-01 |
| Safety, Tolerability, and PK Parameters of Sodium Nitrite Inhalation Solution in Healthy Subjects (NCT01409122) | Aires Pharmaceuticals, Inc. | 2011-07-01 |
| Evaluate The Clinical Effectiveness, Safety And Tolerability Of Sildenafil Used In Doses ≥20mg TID For The Treatment Of Pulmonary Arterial Hypertension (NCT01365585) | Pfizer's Upjohn has merged with Mylan to form Viatris Inc. | 2011-07-01 |
| Iloprost for the Treatment of Pulmonary Hypertension in Adults With Congenital Heart Disease (NCT01319045) | University of California, Los Angeles | 2011-06-01 |
| Extension to CQTI571A2102 to Evaluate Long-term Safety, Tolerability and Efficacy of Imatinib in Severe Pulmonary Arterial Hypertension (PAH) (NCT01392495) | Novartis Pharmaceuticals | 2011-06-01 |
| DelIVery for Pulmonary Arterial Hypertension (PAH) & Continued Support Study (NCT01321073) | Medtronic Cardiac Rhythm and Heart Failure | 2011-06-01 |
| Epoprostenol for Injection in Patients With Pulmonary Arterial Hypertension (NCT01470144) | Actelion | 2011-06-01 |
| Peripheral Muscle Microcirculation and Exercise-induced Blood Flow Distribution in Pulmonary Arterial Hypertension (NCT01520493) | Laval University | 2011-06-01 |
| Pulmonary Arterial Hypertension Quality Enhancement Research Initiative Extension Program (NCT01389206) | Actelion | 2011-06-01 |
| Safely Change From Bosentan to Ambrisentan in Pulmonary Hypertension (NCT01330108) | University of Alabama at Birmingham | 2011-05-01 |
| Pharmacokinetic Effects of QTI571 on Sildenafil and Bosentan in Pulmonary Arterial Hypertension Participants (NCT01392469) | Novartis Pharmaceuticals | 2011-04-20 |
| IV Iron Replacement for Iron Deficiency in Idiopathic Pulmonary Arterial Hypertension (IPAH) Patients (NCT01447628) | Imperial College London | 2011-03-29 |
| FUTURE 3 Study Extension (NCT01338415) | Actelion | 2011-03-08 |
| Effects of Two Dosing Regimens of Bosentan in Children With Pulmonary Arterial Hypertension (NCT01223352) | Actelion | 2011-03-08 |
| Treprostinil Combined With Tadalafil for Pulmonary Hypertension (NCT01302444) | Rhode Island Hospital | 2011-03-01 |
| Study in Subjects With PAH and PH Secondary to IPF Using Inhaled GeNOsyl. (NCT01265888) | Geno LLC | 2011-03-01 |
| Rt Ventricular Substrate Metabolism as a Predictor of Rt Heart Failure in Patients With Pulmonary Arterial Hypertension (NCT01572077) | Ottawa Heart Institute Research Corporation | 2011-01-01 |
| A Study to Assess the Safety and Efficacy of Treprostinil to Facilitate Liver Transplantation in Patients With Portopulmonary Hypertension (NCT01028651) | United Therapeutics | 2011-01-01 |
| Drug Interaction Between Ritonavir And Sitaxsentan (NCT01251848) | Pfizer | 2011-01-01 |
| Study of Incidence of Respiratory Tract AEs in Patients Treated With Tyvaso® Compared to Other FDA Approved PAH Therapies (NCT01266265) | United Therapeutics | 2010-12-01 |
| Effect Of Rifampin On Pharmacokinetics Of Sitaxsentan (NCT01251835) | Pfizer | 2010-12-01 |
| A Pharmacokinetic Drug-Drug Interaction (DDI) Study Between Sitaxsentan And Sildenafil, And Between Sitaxsentan And Tadalafil After Multiple Doses (NCT01244620) | Pfizer | 2010-11-01 |