| The Internet Therapy for Depression Trial (NCT04009135) | Memorial University of Newfoundland | 2019-06-10 |
| The Effect of Soluble Epoxide Hydrolase (SEH) on Depression (NCT05575713) | Nanfang Hospital, Southern Medical University | 2019-06-01 |
| Feasibility and Effectiveness of Delivering CBT Through OPTT for Depression (NCT04478058) | Dr. Nazanin Alavi | 2019-06-01 |
| Cognitive Reappraisal in Adolescents With Major Depression (NCT03957850) | Ludwig-Maximilians - University of Munich | 2019-05-27 |
| The Role of HNKs in the Antidepressant Effect of Ketamine (NCT03977675) | Columbia University | 2019-05-15 |
| ROOM-LIGHT: Effect of a Dynamic Lighting System in Depressed Inpatients (NCT03821506) | University Hospital Bispebjerg and Frederiksberg | 2019-05-15 |
| Comparative Effectiveness of Pharmacogenomics for Treatment of Depression (NCT03749629) | Massachusetts General Hospital | 2019-05-01 |
| Mechanisms of Rumination Change in Adolescent Depression (NCT03859297) | Ohio State University | 2019-05-01 |
| Glabellar Botulinum Toxin Injections for the Treatment of Geriatric Depression (NCT03833063) | Helse Stavanger HF | 2019-05-01 |
| Sleep Subtypes in Adolescent Depression (NCT03742960) | University of Bern | 2019-04-24 |
| Risk and Resiliency Factors in the RCMP: A Prospective Investigation (NCT05527509) | University of Regina | 2019-04-22 |
| Intervention Targeting Motivational Negative Symptoms (NCT04325100) | University of Liege | 2019-04-20 |
| Safety of Liposom With Citalopram in Elderly Patients With Major Depressive Disorder (NCT04975724) | Fidia Farmaceutici s.p.a. | 2019-04-18 |
| Pre-mapping Networks for Brain Stimulation 2 (NCT05260086) | University Medical Center Goettingen | 2019-04-15 |
| Group CBT and Exercise in Management of Depression (NCT03731728) | University of Alberta | 2019-04-15 |
| Floatation-REST (Reduced Environmental Stimulation Therapy) for Anxiety and Depression (NCT03899090) | Laureate Institute for Brain Research, Inc. | 2019-04-08 |
| DIMES - DIgital MEdicine Study for Adults With Schizophrenia, Bipolar I Disorder, or Major Depression Currently Using Aripiprazole (NCT03881449) | Durham VA Medical Center | 2019-04-04 |
| Nitrous Oxide for Major Depressive Disorder (NCT03932825) | Lingjiang Li | 2019-04-01 |
| Blended Care Versus Face-to-Face Therapy for Depression (NCT04337242) | Universitaire Ziekenhuizen KU Leuven | 2019-03-29 |
| Reward Function and Therapy for Late-Life Depression (NCT03688139) | Weill Medical College of Cornell University | 2019-03-14 |
| Music Therapy and Dialysis: A Pilot Investigation Into the Effectiveness of Patient-Selected Music Interventions on Physiological, Psychological, and Quality-of-Life Outcomes (NCT03925168) | Tulane University | 2019-03-08 |
| Treating Smokers With Mental Illness (NCT03822416) | University of Minnesota | 2019-03-01 |
| A Study to Evaluate SAGE-217 in Adult Participants With Major Depressive Disorder (MDD) (NCT03864614) | Biogen | 2019-02-27 |
| Efficacy, Safety and Pharmacokinetic Study of Inhaled Esketamine in Treatment-resistant Depression (NCT03965858) | Celon Pharma SA | 2019-02-25 |
| Lithium Therapeutic Drug Monitoring; Once Daily Vs Twice Daily Dosing and the Impact of Kidney Function (NCT03811860) | Mount Sinai Hospital, Canada | 2019-02-06 |
| Study With Vortioxetine on Emotional Functioning in Patients With Depression (NCT03835715) | H. Lundbeck A/S | 2019-02-05 |
| A Study to Evaluate the Safety, Tolerability, and Efficacy of SAGE-217 Compared to Placebo in Adult Participants With Comorbid Major Depressive Disorder (MDD) and Insomnia (NCT03771664) | Biogen | 2019-02-04 |
| Vortioxetine in the Elderly vs. Selective Serotonin Reuptake Inhibitors (SSRIs): a Pragmatic Assessment (NCT03779789) | Azienda Ospedaliera Universitaria Integrata Verona | 2019-02-01 |
| Contact: Developing New Clinical Management Strategies (NCT03812588) | New York State Psychiatric Institute | 2019-01-30 |
| The Role of Sex Steroids and Serotonin Brain Dynamics in Perinatal Mental Health (NCT03795688) | Vibe G Frøkjær, MD, PhD | 2019-01-24 |
| Nitrous Oxide for the Treatment of Major Depressive Disorder (NCT03869736) | Bayside Health | 2019-01-22 |
| Efficacy of Light Therapy Device LUMINETTE® in Major Depressive Disorder (NCT03685942) | Centre Psychothérapique de Nancy | 2019-01-16 |
| A Relative Bioavailability Food Effect Study of LY03005 (NCT03822065) | Luye Pharma Group Ltd. | 2019-01-16 |
| Magnetic Randomized Trial in Elderly Depressed (NCT04842929) | University of Sao Paulo | 2019-01-16 |
| L-DOPA vs. Placebo for Depression and Psychomotor Slowing in Older Adults (NCT03761030) | New York State Psychiatric Institute | 2019-01-09 |
| Near Infrared Spectroscopy (NIRS) for Assessment of Depression (NCT04061148) | University of California, San Francisco | 2019-01-04 |
| Ketamine Associated ACC GABA and Glutamate Change and Depression Remission: (NCT03573349) | Mayo Clinic | 2019-01-03 |
| Tracking Response to Antidepressants in Advance of Investigational Trials (NCT04748276) | Adams Clinical | 2019-01-02 |
| Pharmacogenetics of Antidepressant-Induced Disinhibition (NCT03953014) | University of Calgary | 2019-01-02 |
| Repetitive Transcranial Magnetic Stimulation in Pharmaco-naïve Patients With Major Depression (NCT04000022) | University Hospital, Bonn | 2019-01-01 |
| Study on the Effect of PRKCB1 Modulating Inflammatory Factors and the Role for Developing Major Depressive Disorder (NCT03899194) | Shanghai Mental Health Center | 2019-01-01 |
| Brainsway DTMS for Treatment of MDD Using iTBS (NCT04679753) | Brainsway | 2019-01-01 |
| Transcranial Magnetic Stimulation in Patients With a Depressive Episode - RCT Trial (NCT05543421) | Wroclaw Medical University | 2019-01-01 |
| A Transdiagnostic Sleep and Circadian Treatment for Major Depressive Disorder (NCT03786731) | Chinese University of Hong Kong | 2019-01-01 |
| Simvastatin as an Augmentation Treatment for Treatment Resistant Depression: Randomized Controlled Trial. (NCT03435744) | Pakistan Institute of Living and Learning | 2019-01-01 |
| Ketamine for Major Depressive Disorder (NCT03721900) | Shenox Pharmaceuticals, LLC | 2018-12-28 |
| Efficacy of Pythagorean Self-Awareness Intervention for Major Depressive Disorder (NCT04536714) | Evgenia E. Psarraki | 2018-12-03 |
| A Pilot Study of Prophylactic Management of Lamotrigine in Pregnant Women (NCT03774641) | Johns Hopkins University | 2018-12-03 |
| Vortioxetine Intravenous Infusion at Initiation of Oral Treatment With Vortioxetine in Patients With Depression (NCT03766867) | H. Lundbeck A/S | 2018-12-03 |
| Treatment for Cognitive Impairment in Depression (NCT04317001) | Stanford University | 2018-12-01 |
| Efficacy and Safety of Accelerated Transcranial Magnetic Stimulation With H1-coil (dTMS) (NCT03718013) | Sveti Ivan Psychiatric Hospital | 2018-12-01 |
| Influence of rTMS on Symptoms and Cognitive Function in Patients With Psychiatric Disorders (NCT04055181) | Beijing HuiLongGuan Hospital | 2018-12-01 |
| Study to Explore the Effective Doses and to Assess the Safety and Efficacy of Hypidone Hydrochloride Tablets (NCT03739632) | Zhejiang Huahai Pharmaceutical Co., Ltd. | 2018-11-30 |
| Inflammatory Markers as Predictors of the Efficacy of Electroconvulsive Therapy (ECT) in Major Depression Patients (NCT06439797) | The Chaim Sheba Medical Center | 2018-11-29 |
| A Study to Evaluate the Efficacy of SAGE-217 in the Treatment of Adult Participants With Major Depressive Disorder (NCT03672175) | Biogen | 2018-11-19 |
| Salicylic Augmentation in Depression (NCT03152409) | Jessica Harder | 2018-11-15 |
| EXperimental Paradigm to Investigate Expectation Change in Depression 4 (NCT03780881) | Philipps University Marburg | 2018-11-11 |
| The Objective of This Study is to Evaluate the Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone (NCT03739203) | AbbVie | 2018-11-10 |
| Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) Who Have Had an Inadequate Response to Antidepressants Alone (NCT03738215) | AbbVie | 2018-11-09 |
| Zelquistinel in the Treatment of Adults With Major Depressive Disorder (NCT03726658) | Syndeio Biosciences, Inc | 2018-11-08 |
| Universal vs. Targeted School Screening for Adolescent Major Depressive Disorder (NCT03716869) | Milton S. Hershey Medical Center | 2018-11-06 |
| Characterization of Microbial, Immune and Epigenetic Biomarkers for Major Depressive Disorder and ECT Treatment (NCT03703414) | Ziv Hospital | 2018-11-01 |
| Group Metacognitive Therapy vs Clinical Management for Depression (NCT03711123) | University of Oslo | 2018-11-01 |
| Investigating Predictors of Treatment Response in Treatment-Resistant Depression (TRD) With Interleaved TMS/fMRI (NCT03642522) | University of British Columbia | 2018-11-01 |
| Nitrous Oxide- Suicidal Ideation (NCT03736538) | Washington University School of Medicine | 2018-10-30 |
| Research on the Effects of Combined Neurostimulation Protocols on Stress (NCT03722095) | University Ghent | 2018-10-29 |
| Fecal Microbiota Transplantation in Depression (NCT03281044) | Psychiatric Hospital of the University of Basel | 2018-10-24 |
| Deep TMS for Comorbid Depression and Cognitive Impairment in Older Adults (NCT03665831) | Rotman Research Institute at Baycrest | 2018-10-23 |
| Sensory and Psychomotor Profile in Depression (NCT04031937) | Centre Hospitalier Esquirol | 2018-10-23 |
| Modafinil's Effects on Cognition in Remitted MDD (NCT03620253) | Unity Health Toronto | 2018-10-15 |
| A Long-Term Study of Brexpiprazole in Patients With Major Depressive Disorder (NCT03737474) | Otsuka Pharmaceutical Co., Ltd. | 2018-10-04 |
| Biomarkers in Repetitive Transcranial Magnetic Stimulation (rTMS) for Adolescent Depression (NCT03363919) | Mayo Clinic | 2018-09-24 |
| Maintenance of Response After rTMS for Depression Using tDCS (NCT03708159) | Centre for Addiction and Mental Health | 2018-09-24 |
| Single Session of tACS in a Depressive Episode (NCT03449979) | University of North Carolina, Chapel Hill | 2018-09-19 |
| Primary-Care Based Mindfulness Intervention (NCT03922581) | Emory University | 2018-09-14 |
| Pharmacogenomic-Guided Antidepressant Drug Prescribing in Cancer Patients (NCT03674138) | H. Lee Moffitt Cancer Center and Research Institute | 2018-09-12 |
| Using a Low Dose of Ketamine vs. Active Placebo in Treating Severe Depression and Suicide (NCT03666390) | Taipei Veterans General Hospital, Taiwan | 2018-09-10 |
| Cycloserine rTMS Plasticity Augmentation in Depression (NCT03511599) | University of Calgary | 2018-09-03 |
| A Neurosteroid Intervention for Menopausal and Perimenopausal Depression (NCT03505905) | University of Texas Southwestern Medical Center | 2018-09-01 |
| An Eye Tracking Study of Affective Disorder Patients With Suicide Risk (NCT03711045) | Central South University | 2018-09-01 |
| Identification of Multi-modal Bio-markers for Early Diagnosis and Treatment Prediction in Schizophrenia Individuals (NCT03790085) | Tianjin Medical University General Hospital | 2018-09-01 |
| Spinal Cord Stimulation for the Treatment of Major Depressive Disorder (NCT03433339) | University of Cincinnati | 2018-08-29 |
| The Effect of Celecoxib on Neuroinflammation in MDD (NCT04814355) | Stony Brook University | 2018-08-01 |
| A Prediction Study of Multiple Indexes of the Effect of Different Mechanisms of Antidepressants Treatment on Depression (NCT03623711) | Yuqi Cheng | 2018-08-01 |
| The Antidepressant Advisor Study (NCT03628027) | King's College London | 2018-08-01 |
| The Antidepressant Advisor (Study 3): fMRI Study to Predict Treatment Response in Patients With Depression (NCT04342299) | King's College London | 2018-08-01 |
| Transcranial Magnetic Stimulation Study of Cortical Excitability as Marker of Antidepressant Response: EXCIPSY Study (NCT03606850) | Centre Hospitalier du Rouvray | 2018-07-30 |
| A Study of Brexpiprazole in Patients With Major Depressive Disorder (NCT03697603) | Otsuka Pharmaceutical Co., Ltd. | 2018-07-30 |
| A Trial to Evaluate the Efficacy, Safety & Tolerability of Brexpiprazole in the Maintenance Treatment of Adults With Major Depressive Disorder (NCT03538691) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2018-07-13 |
| Modeling Multi-level Dyadic Behavior to Transform the Science and Practice of Psychotherapy Process and Outcome. (NCT03594773) | University of Pittsburgh | 2018-07-08 |
| Efficacy, Safety, and Tolerability of Levomilnacipran ER in Pediatric Patients (7-17 Years) With Major Depressive Disorder (NCT03569475) | Allergan | 2018-07-06 |
| MARt-Depression Trial (NCT03564067) | Centre for Addiction and Mental Health | 2018-07-05 |
| Brain Hippocampal Volume Relationship With Anxious Symptoms in Major Depressive Patients (NCT04430556) | Hospital Universitario Dr. Jose E. Gonzalez | 2018-07-01 |
| A Trial to Measure the Difference in All-cause Hospitalizations for Participants Who Are Using Abilify MyCite Versus Virtual Matched Controls in Adults With Schizophrenia, Bipolar 1 Disorder, and Major Depressive Disorder (NCT03643159) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2018-06-28 |
| A Study of LY03005 vs Pristiq (NCT03733574) | Luye Pharma Group Ltd. | 2018-06-19 |
| The Safety and Efficacy of Brexpiprazole as Adjunctive Therapy in the Treatment of Major Depressive Disorder (NCT03487198) | Otsuka Beijing Research Institute | 2018-05-30 |
| Assessing Symptomatic Clinical Episodes in Depression (NCT03595579) | Axsome Therapeutics, Inc. | 2018-05-30 |
| Effect of Food, Gender, and Age on the Pharmacokinetic Profile of SUVN-911 in Healthy Subjects (NCT03551288) | Suven Life Sciences Limited | 2018-05-22 |
| The Role of Cognitive Control in the Transdiagnostic Conceptualization of "Intrusive Thoughts" (NCT03414619) | Massachusetts General Hospital | 2018-05-18 |
| Concurrent fMRI-guided rTMS and Cognitive Therapy for the Treatment of Major Depressive Episodes (NCT03289923) | National Institute of Mental Health (NIMH) | 2018-05-17 |