| Integrated Chronotherapy for Perinatal Depression (NCT02053649) | Rhode Island Hospital | 2014-01-01 |
| The Effect of Ketamine on Mechanises Underlying Suicidal Ideation and Drug-resistant Major Depression (NCT02037503) | Tel-Aviv Sourasky Medical Center | 2014-01-01 |
| Integral Assessment in Unipolar Depression (NCT02268487) | University of Sao Paulo | 2014-01-01 |
| Deep Brain Stimulation (DBS) Therapy for Treatment Resistant Depression (NCT02046330) | The University of Texas Health Science Center, Houston | 2013-12-16 |
| Games to Overcome Late Life Depression (NCT02229188) | University of Washington | 2013-12-01 |
| PET Imaging of Brain mGluR1 Receptors Using [18F]FIMX (NCT02230592) | National Institute of Mental Health (NIMH) | 2013-11-08 |
| Brexpiprazole (OPC-34712) as an Adjunctive Treatment in Adults With Major Depressive Disorder and Anxiety Symptoms (NCT02013531) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2013-11-01 |
| A Randomized, Double-Blind, Placebo-Controlled, Sequential Parallel Study of CERC-301 in the Adjunctive Treatment of Subjects With Severe Depression and Recent Active Suicidal Ideation Despite Antidepressant Treatment (NCT01941043) | Avalo Therapeutics, Inc. | 2013-11-01 |
| Evaluation of a Mental Health Physician Support Program in Nova Scotia (NCT01975948) | Nova Scotia Health Authority | 2013-11-01 |
| Long-term Safety and Tolerability Study of Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder (NCT01944969) | H. Lundbeck A/S | 2013-10-01 |
| Using Mental Health Telemetry to Predict Relapse and Re-hospitalization in Mood Disorders (NCT01882608) | Dr. David Kreindler | 2013-10-01 |
| A Study of Sustained-Release Desvenlafaxine Hydrochloride for the Treatment of Major Depressive Disorder (NCT01977378) | Jiangsu Hansoh Pharmaceutical Co., Ltd. | 2013-10-01 |
| Trial of a Positive Psychology Intervention in Major Depressive Disorder (NCT02004145) | Massachusetts General Hospital | 2013-10-01 |
| Study of Brexpiprazole as Adjunctive Treatment of Irritability in Patients With Major Depressive Disorder and an Inadequate Response to Antidepressant Therapy (NCT01942785) | H. Lundbeck A/S | 2013-10-01 |
| Escitalopram, Placebo and tDCS in Depression: a Non-inferiority Trial (NCT01894815) | University of Sao Paulo | 2013-10-01 |
| Brain Mechanisms of Human Motivation (NCT01976975) | Mclean Hospital | 2013-10-01 |
| Safety and Efficacy Study Comparing ETS6103 With Amitriptyline in the Treatment of Major Depressive Disorder (MDD) (NCT02014363) | e-Therapeutics PLC | 2013-10-01 |
| Neuronal Responses to Social Feedback in Major Depressive Disorder (NCT02180607) | University of Michigan | 2013-10-01 |
| Maintaining Mechanisms of Chronic Depression and Their Changeability (NCT02801513) | Freie Universität Berlin | 2013-09-01 |
| Double-blind Pilot Trial of Mirtazapine for the Treatment of Co-occurring AD/MDD. (NCT02185131) | University of Pittsburgh | 2013-09-01 |
| Randomized Controlled Trial of Conventional vs Theta Burst rTMS (NCT01887782) | Centre for Addiction and Mental Health | 2013-09-01 |
| MRS and Medication Response: A Pilot Study (NCT03254342) | Stanford University | 2013-08-06 |
| Effects of Treatment on Decision-making in Major Depression (NCT01916824) | Emory University | 2013-08-01 |
| Cognitive Training for Depression II (NCT01934491) | Icahn School of Medicine at Mount Sinai | 2013-08-01 |
| A Comparison of Medication Augmentation and PST in the Treatment of Depression in Older Adults (NCT01942187) | New York State Psychiatric Institute | 2013-08-01 |
| Safety and Efficacy of Vilazodone in Adolescent Patients With Major Depressive Disorder (NCT01878292) | Forest Laboratories | 2013-07-11 |
| Detecting Depression and Bipolar Disorder in Adolescents Using a Biomarker Panel (NCT01957501) | University of Utah | 2013-07-01 |
| A Randomised Controlled Clinical Trial of Memory Specificity Training (MEST) for Depression (NCT01882452) | Medical Research Council | 2013-07-01 |
| Identifying Biological Markers for Severe Depression (NCT01831882) | Stanford University | 2013-07-01 |
| Comparison of Two tDCS Protocols for the Treatment of Major Depressive Disorder (NCT01877447) | University of Sao Paulo | 2013-07-01 |
| Electrophysiologic Parameters and Biomarkers Predicting Treatment Response in Patients With Major Depressive Disorder (NCT01997580) | Seoul National University Bundang Hospital | 2013-07-01 |
| Nuedexta in Treatment-Resistant Major Depression (NCT01882829) | James Murrough | 2013-07-01 |
| Frontal Hypoperfusion Effects on Antidepressant Outcomes in Late-Life Depression (NCT01896934) | Vanderbilt University | 2013-07-01 |
| Comparative Effectiveness Clinical Trial of MST Compared to ECT in Major Depressive Disorder (NCT04216095) | Tanta University | 2013-06-07 |
| Low-Dose Naltrexone (LDN) for Depression Relapse and Recurrence (NCT01874951) | Massachusetts General Hospital | 2013-06-01 |
| An Open Prospective Trial of IV Ketamine in Suicidal Adolescents (NCT02048423) | Nationwide Children's Hospital | 2013-06-01 |
| Maintenance Transcranial Electrical Stimulation for Depression (NCT01890356) | The University of New South Wales | 2013-06-01 |
| Effect of Intranasal Insulin on Depressive Symptoms in Major Depressive Disorder (NCT00570050) | University Health Network, Toronto | 2013-06-01 |
| Physician Survey on Monitoring of Patients Treated With Quetiapine (NCT01795326) | AstraZeneca | 2013-06-01 |
| A Health Intervention to Prevent Depression Hepatitis C Patients (NCT01890083) | University of Texas Southwestern Medical Center | 2013-06-01 |
| Brexpiprazole as Adjunctive Treatment in Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment (NCT01838681) | H. Lundbeck A/S | 2013-06-01 |
| Deep rTMS for Treatment-Resistant Late-life Depression (NCT01860157) | Centre for Addiction and Mental Health | 2013-06-01 |
| A Study of Fluoxetine in Major Depressive Disorder (MDD) Long-Term Dosing (NCT01808651) | Eli Lilly and Company | 2013-05-01 |
| Double-Blind Treatment of Major Depressive Disorder With Vilazodone (NCT01742832) | University of Chicago | 2013-05-01 |
| Blame Rebalance fMRI Feedback Proof-of-concept (NCT01920490) | D'Or Institute for Research and Education | 2013-05-01 |
| Long-term Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy in Patients With Major Depressive Disorder (NCT01838876) | Forest Laboratories | 2013-04-29 |
| Evaluation of the Safety and Pharmacokinetics of MSI-195 to a Commercial S-Adenosylmethionine (NCT04623034) | MSI Methylation Sciences, Inc. | 2013-04-17 |
| Neural Predictors and Longitudinal Neural Correlates of Deep Transcranial Magnetic Stimulation for Treating Major Depression (NCT01409317) | Douglas Mental Health University Institute | 2013-04-01 |
| rTMS for Depressed Teens: A Sham-Controlled Trial, Part 1 (NCT01804270) | Paul E. Croarkin | 2013-04-01 |
| The Effects of Vilazodone on Glutamate in the Anterior Cingulate Cortex in Anxious Unipolar Depressives (NCT02028026) | Massachusetts General Hospital | 2013-04-01 |
| Efficacy and Safety of Brexpiprazole as Adjunctive Treatment in Elderly Patients With Major Depressive Disorder With an Inadequate Response to Antidepressant Treatment (NCT01837797) | H. Lundbeck A/S | 2013-04-01 |
| Genetic and Neural Predictors of Adolescent Depression (NCT01743716) | Mclean Hospital | 2013-04-01 |
| Can Genetics Predict Treatment Response to a Computerized Self-help Program for Depression? (NCT01818453) | University of Texas at Austin | 2013-03-01 |
| A Study of Fluoxetine in Major Depressive Disorder (MDD) Short-Term Dosing (NCT01808612) | Eli Lilly and Company | 2013-03-01 |
| rTMS for Depressed Teens: A Sham-Controlled Trial, Part 2 (NCT01804296) | Paul E. Croarkin | 2013-03-01 |
| HPA Axis Activity Due To Early Traumatic Stress and Metabolic Symptoms (NCT02398877) | Charite University, Berlin, Germany | 2013-02-01 |
| Comparative Study of Physiological and Cerebrovascular Reactivity in Depression, at the Three Phases of Emotion (NCT02026622) | University Hospital, Tours | 2013-02-01 |
| Riluzole Augmentation Pilot in Depression (RAPID) Trial (NCT01703039) | Brigham and Women's Hospital | 2013-01-01 |
| Ketamine Versus Placebo for Treatment Resistant Major Depressive Disorder (NCT01667926) | Massachusetts General Hospital | 2013-01-01 |
| The Efficacy And Cognitive Impairment Of Modified Electroconvulsive Therapy (NCT02066077) | Shanghai Mental Health Center | 2013-01-01 |
| Comparison of Behavioral Activation and Antidepressant Medication in the Treatment of Adolescents With Depression (NCT01740726) | Emory University | 2013-01-01 |
| Does Vilazodone Help With Antidepressant-associated Sexual Dysfunction? (NCT01856127) | Thomas Jefferson University | 2013-01-01 |
| Systematic Genetic Analysis of Phenomenology and Treatment Response in Mood Disorders (NCT01769859) | University Hospitals Cleveland Medical Center | 2013-01-01 |
| Lifestyle Intervention for Diabetes and Weight Management in Psychosis (NCT01828931) | Centre for Addiction and Mental Health | 2012-12-01 |
| Trazodone Once a Day in Major Depression Disorder (NCT02086929) | Aziende Chimiche Riunite Angelini Francesco S.p.A | 2012-12-01 |
| Differential Efficacy of Supportive and Interpretative Psychodynamic Techniques for Dependent and Self-critical Depressive Patients (NCT01640483) | University Ghent | 2012-12-01 |
| VA Augmentation and Switching Treatments for Improving Depression Outcomes (NCT01421342) | VA Office of Research and Development | 2012-12-01 |
| Efficacy, Safety and Tolerability of Cariprazine as an Adjunctive Treatment to Antidepressant Therapy (ADT) in Patients With Major Depressive Disorder (MDD) (NCT01715805) | Forest Laboratories | 2012-11-15 |
| Neurophysiologic Correlates of Hypersomnia (NCT01719315) | University of Wisconsin, Madison | 2012-11-01 |
| Nitrous Oxide as Treatment for Major Depression - a Pilot Study (NCT02139540) | Washington University School of Medicine | 2012-11-01 |
| Study of the Efficacy and Safety of LY2940094 in Participants With Major Depressive Disorder (MDD) (NCT01724112) | BlackThorn Therapeutics, Inc. | 2012-11-01 |
| Transcranial Magnetic Stimulation for Adolescent Depression (NCT01731678) | University of Calgary | 2012-11-01 |
| Efficacy and Safety of GLYX-13 in Subjects With Inadequate/Partial Response to Antidepressants (NCT01684163) | Naurex, Inc, an affiliate of Allergan plc | 2012-11-01 |
| Neurobiological Bases of Placebo Response in Major Depressive Disorder (NCT01787240) | Massachusetts General Hospital | 2012-11-01 |
| A Dose Escalation Phase I Study of PDC-1421 Capsule Targeting in Depression (NCT01774045) | BioLite, Inc. | 2012-11-01 |
| Sensitivity of Short and Long Allele Carriers of the 5-HTTLPR to Environmental Threat Post Hydrocortisone Administration (NCT01710202) | University of Texas at Austin | 2012-10-01 |
| Efficacy of Electronic Cognitive Behavioral Therapy Application to Treat Major Depressive Disorder (NCT01752608) | MindApps | 2012-10-01 |
| Effectiveness of Buddhist Monks in Providing Cognitive Behavior Therapy (NCT01706731) | Chiang Mai University | 2012-10-01 |
| Brief Multifamily Psychoeducation for Families of Patients With Chronic Major Depression (NCT01734291) | Nagoya City University | 2012-10-01 |
| Mindfulness-Based Cognitive Therapy for Perinatal Women With Mood Disorders (NCT02150681) | University of California, Los Angeles | 2012-10-01 |
| Internet Based Cognitive Behavioral Therapy Effects on Depressive Cognitions and Brain Function (NCT01598922) | Mclean Hospital | 2012-10-01 |
| Accelerated rTMS for Treatment-Resistant Major Depression (NCT02125799) | Douglas Mental Health University Institute | 2012-10-01 |
| Neural Components Underlying the Treatment of Adolescent Depression (NCT01717508) | Mclean Hospital | 2012-10-01 |
| Incidence of Metabolic Syndrome and Thyroid Dysfunction in Patients With Major Depressive Disorder (NCT01682785) | Chiang Mai University | 2012-09-01 |
| A Study of JNJ-40411813 as Supplementary Treatment to an Antidepressant in Adults With Depression and Anxiety Symptoms (NCT01582815) | Janssen Research & Development, LLC | 2012-09-01 |
| The Study of Antidepressant Properties and Safety of Fer-01(Soline®) on the Patients With Depression (NCT01671124) | Taipei Medical University Hospital | 2012-09-01 |
| Developing New Clinical Management Strategies (NCT02082392) | New York State Psychiatric Institute | 2012-09-01 |
| Brain Imaging of rTMS Treatment for Depression (NCT01829165) | Stanford University | 2012-09-01 |
| Creatine Augmentation in Veterans With SSRI-Resistant Major Depression (NCT01175616) | University of Utah | 2012-09-01 |
| Investigate Efficacy & Safety of RO4995819 vs. Placebo as Adjunct Tx in Patients w/Major Depressive Disorder (NCT01733654) | Stanford University | 2012-09-01 |
| A Study of Ketamine in Patients With Treatment-resistant Depression (NCT01627782) | Janssen Research & Development, LLC | 2012-08-06 |
| Role of Inflammation Factors and Insulin Resistance in Major Depressive Disorder (NCT01699490) | National Cheng-Kung University Hospital | 2012-08-01 |
| Inflammation and Electroconvulsive Therapy (NCT02095639) | Centre for Addiction and Mental Health | 2012-08-01 |
| Computerized Cognitive Remediation for Geriatric Depression (NCT01979289) | Weill Medical College of Cornell University | 2012-08-01 |
| Phospholipid Hypothesis of Depression: From Molecular Biology, Neuroimaging to Behaviour (NCT02615405) | National Science and Technology Council, Taiwan | 2012-08-01 |
| Study of Placebo Without Deception Versus Standard Antidepressant for Major Depressive Disorder (NCT01650740) | Sunnybrook Health Sciences Centre | 2012-08-01 |
| Treatment for Depressed, Obese Individuals at Risk for Cardiovascular Disease (CVD) (NCT01692574) | University of Pennsylvania | 2012-08-01 |
| The Effectiveness of rTMS in Depressed VA Patients (NCT01191333) | VA Office of Research and Development | 2012-07-02 |
| Vilazodone for Treatment of Geriatric Depression (NCT01608295) | University of California, Los Angeles | 2012-07-01 |
| Phase 1 Study to Assess the Safety/Tolerability of Brexpiprazole as Adjunctive Therapy in Elderly Subjects With Major Depressive Disorder (NCT01670279) | Otsuka Pharmaceutical Development & Commercialization, Inc. | 2012-07-01 |