| A First-in-human Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of AZD2373 After Single Dose Administration in Healthy Male Subjects of African Ancestry. (NCT04269031) | AstraZeneca | 2020-02-13 |
| Study of the Effects of Itraconazole and Rifampin on LOXO-305 in Healthy Participants (NCT05134337) | Loxo Oncology, Inc. | 2020-02-12 |
| Omadacycline Tissue Penetration in Diabetic Patients With Wound Infections and Healthy Volunteers Via In Vivo Microdialysis (NCT04144374) | Hartford Hospital | 2020-02-10 |
| Effect of Tebipenem on Normal Human Intestinal Microbiota (NCT04376554) | Spero Therapeutics | 2020-02-10 |
| Study of the Effect of Food and a Proton Pump Inhibitor (PPI; Omeprazole) on LOXO-305 in Healthy Participants (NCT05134350) | Loxo Oncology, Inc. | 2020-02-06 |
| Investigation of the Gut Microbiome and Statin Response (NCT04098003) | Sony Tuteja | 2020-02-06 |
| A Drug-Drug Interaction Study To Estimate The Effect Of Tafamidis On Rosuvastatin Pharmacokinetics (NCT04253353) | Pfizer | 2020-02-06 |
| Generation of Biological Samples Positive to Testosterone for Anti-doping Control (NCT04207684) | Parc de Salut Mar | 2020-02-04 |
| A Study to Determine the Safety of AV-1, an Antibody Being Developed for Treatment of Dengue, in Healthy Volunteers (NCT04273217) | AbViro LLC | 2020-02-04 |
| A Study of Single Ascending Doses of STAR-101 in Healthy Participants (NCT04081597) | Acanthas Pharma Inc | 2020-02-01 |
| A Research Study Looking at the Comparability (Bioequivalence) of Two Versions of Semaglutide (NCT04228354) | Novo Nordisk A/S | 2020-01-29 |
| VNRX-7145 SAD/MAD Safety and PK in Healthy Adult Volunteers (NCT04243863) | Basilea Pharmaceutica | 2020-01-20 |
| Evaluation of the Safety and Tolerability of CKD-510 in Healthy Subjects (NCT04746287) | Chong Kun Dang Pharmaceutical | 2020-01-14 |
| A Research Study Investigating Mim8 in People With Haemophilia A (NCT04204408) | Novo Nordisk A/S | 2020-01-10 |
| A Study to Evaluate the Safety, Tolerability, Pharmacokinetics, Pharmacodynamics, Bioavailability, and Food-effects of EA1080 in Healthy Caucasian and Japanese Male Participants (NCT04223960) | EA Pharma Co., Ltd. | 2020-01-09 |
| Safety, Tolerability and Pharmacokinetics of HSK21542 in Healthy Volunteers (NCT04213196) | Sichuan Haisco Pharmaceutical Group Co., Ltd | 2020-01-09 |
| A Study to Investigate the Use of Delayed Release Tablets for Colonic Delivery of Brilacidin in Healthy Volunteers (NCT04240223) | Innovation Pharmaceuticals, Inc. | 2020-01-06 |
| Pharmacokinetic and Mass Balance Study of Orally Administered [14C]-AZD4205 in Healthy Adult Male Volunteers (NCT04225208) | Dizal Pharmaceuticals | 2020-01-06 |
| A Study to Evaluate the Effect of Pharmacokinetics (PK) of Acalabrutinib and Its Active Metabolite (ACP-5862) When Administered Alone and With Moderate CYP3A4 Inhibitors Fluconazole or Isavuconazole in Healthy Adult Participants (NCT05140096) | Acerta Pharma BV | 2020-01-03 |
| Human Skin and Gut Mycobiome and Bacteriome Comprehensive Registry (NCT05196061) | University Hospitals Cleveland Medical Center | 2020-01-01 |
| Immunogenicity and Safety of an Investigational Quadrivalent Meningococcal Conjugate Vaccine in Healthy Adults, Adolescents, Children, and Toddlers in India and Healthy Adolescents and Children in the Republic of South Africa (NCT04143061) | Sanofi Pasteur, a Sanofi Company | 2019-12-30 |
| A Study to Evaluate the Safety, Tolerability and Amount of EI-1071 in Blood in Healthy Volunteers (NCT04238364) | Elixiron Immunotherapeutics Inc. | 2019-12-27 |
| A Study to Assess Effect of Exercise Program Provided by Smartphone Application on the Body Composition (NCT04194697) | Astellas Pharma Inc | 2019-12-25 |
| A Study With [18F]MNI-1054 to Determine Lysine -Specific Demethylase 1A (LSD1) Brain Enzyme Occupancy of TAK-418 After Single-Dose Oral Administration in Healthy Participants (NCT04202497) | Takeda | 2019-12-18 |
| Influence of Fedratinib on the Pharmacokinetics of the Transporter Probe Substrates Digoxin, Rosuvastatin, and Metformin (NCT04231435) | Celgene | 2019-12-18 |
| Assessment of Exercise Capacity in Virtual Reality (NCT04197024) | The Opole University of Technology | 2019-12-17 |
| ANG-3070 in Healthy Adult Participants (NCT04196179) | Angion Biomedica Corp | 2019-12-17 |
| Pharmacokinetic and Tolerance Study of Meloxicam Eye Drops in Healthy Volunteers (NCT04322175) | Beijing Tongren Hospital | 2019-12-16 |
| A Study to Assess Safety, Tolerability, Pharmacokinetics (PK), Immunogenicity, and Pharmacodynamics (PD) of Intravenous Infusions of E2814 in Healthy Participants (NCT04231513) | Eisai Inc. | 2019-12-16 |
| Mass Balance Recovery, Metabolite Profile and Metabolite Identification of [14C]-MD1003 in Healthy Male Subjects (NCT04223232) | MedDay Pharmaceuticals SA | 2019-12-10 |
| A First-in-Human Study of Single and Multiple Doses of anle138b in Healthy Subjects (NCT04208152) | MODAG GmbH | 2019-12-06 |
| Safety, Tolerability, Pharmacokinetics, Pharmacodynamics of GSK2330811 in Healthy Japanese Participants (NCT04138043) | GlaxoSmithKline | 2019-12-05 |
| A Study to Evaluate the Pharmacokinetics and Safety of ASP015K in Healthy Chinese Subjects (NCT04143477) | Astellas Pharma China, Inc. | 2019-12-05 |
| Comparison of Injection Site Pain Experience for Semaglutide and Dulaglutide sc (NCT04189848) | Novo Nordisk A/S | 2019-12-03 |
| Bioequivalence of Solid/Crushed/Dissolved Forms of Biktarvy® (NCT04244448) | University Hospital, Caen | 2019-12-02 |
| Physiological Changes Exploration During the Hypnotic State (NCT04020731) | University Hospital, Grenoble | 2019-12-01 |
| A Study to Evaluate Nicotine Uptake and Biomarkers in Adult Smokers Using mybluTM Electronic Cigarettes (NCT04429932) | Fontem US LLC | 2019-12-01 |
| Behavioral and Physiological Effects of THC and CBD (NCT03832816) | Johns Hopkins University | 2019-12-01 |
| A Research Study Looking at Similarity Between Once-weekly Semaglutide Versions for Different Injection Pens (NCT04152915) | Novo Nordisk A/S | 2019-11-25 |
| The Role of Gut Microbiome on Cardiovascular Health Benefits of Dietary Lignans (CardioFlax Study). (NCT04179136) | King's College London | 2019-11-25 |
| Generation of Biological Samples Positive to Hydromorphone for Anti-doping Control (NCT04081376) | Parc de Salut Mar | 2019-11-20 |
| A Study to Explore Pharmacodynamic Effects of BIIB104 on Brain Circuitry in Healthy Participants (NCT04068532) | Biogen | 2019-11-15 |
| A Study to Evaluate the Pharmacokinetics (PK), Safety and Tolerability of TAK-123 After Intravenous Infusion in Japanese Healthy Adult Male Participants (NCT04155567) | Takeda | 2019-11-13 |
| Study to Evaluate the Drug-drug Interactions Between Metformin and AMG 510 in Healthy Participants (NCT05550129) | Amgen | 2019-11-13 |
| TQT2 Study to Evaluate the Effect of MD1003 on Cardiac Repolarization in Healthy Adult Subjects (NCT04168723) | MedDay Pharmaceuticals SA | 2019-11-11 |
| Study to Evaluate HL-TOF Tab. 5 mg Compared With XelJanz Tab. in Healthy Volunteers (NCT04114461) | Hanlim Pharm. Co., Ltd. | 2019-11-06 |
| Closed-loop Control of Penicillin Delivery (NCT04053140) | Imperial College London | 2019-11-05 |
| A Study to Evaluate Nicotine Uptake and Biomarkers in Smokers Using mybluTM Electronic Cigarettes (NCT04430634) | Fontem US LLC | 2019-11-01 |
| Study to Assess the Immune Response and the Safety Profile of a High-Dose Quadrivalent Influenza Vaccine (QIV-HD) Compared to a Standard-Dose Quadrivalent Influenza Vaccine (QIV-SD) in Europeans Adults 60 Years of Age and Older (NCT04024228) | Sanofi Pasteur, a Sanofi Company | 2019-10-28 |
| A Study Comparing the Pharmacokinetics and Palatability of Two Candidate Pediatric Powder-for-Oral-Suspension Formulations of Maribavir to the Current Maribavir Tablet Formulation Administered in Healthy Adult Participants (NCT04131556) | Shire | 2019-10-25 |
| Generation of Biological Samples Positive to Somatropin for Anti-doping Control (NCT04042428) | Parc de Salut Mar | 2019-10-25 |
| Evaluation of Lung Volume Under Nasal High Flow With a Time of Flight Camera (NCT04096183) | University Hospital, Brest | 2019-10-24 |
| Safety Evaluation of β-arbutin in Healthy Human Subjects (NCT03868748) | SP Nutraceuticals Inc. | 2019-10-23 |
| Effects of Crofelemer on the Gut Microbiome in Healthy Volunteers and in HIV+ Patients With Non-Infectious Diarrhea (NCT04192487) | Napo Pharmaceuticals, Inc. | 2019-10-22 |
| Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of Single Ascending Doses of KPL-404 in Healthy Subjects (NCT04497662) | Kiniksa Pharmaceuticals, Ltd. | 2019-10-22 |
| Study of Purified Vero Rabies Vaccine Compared With Two Reference Rabies Vaccines, Given in a Pre-exposure Regimen to Children and Adults and as Single Booster Dose to a Subset of Adults (NCT04127786) | Sanofi Pasteur, a Sanofi Company | 2019-10-21 |
| A Double-blind Randomized Placebo-controlled Study Study of the Safety, Reactogenicity and Immunogenicity of the GamFluVac (NCT04034290) | Gamaleya Research Institute of Epidemiology and Microbiology, Health Ministry of the Russian Federation | 2019-10-18 |
| A Study to Evaluate the Effect of Single-Dose Intravenous Rifampin as a Prototypic Inhibitor of Organic Anion Transporting Polypeptide (OATP) 1B1 and OATP1B3 on the Single-Dose Pharmacokinetics (PK) of Oral TAK-906 in Healthy Adult Participants (NCT04121078) | Millennium Pharmaceuticals, Inc. | 2019-10-15 |
| Japanese Pharmacokinetic Bridging Study for CC-93538 (NCT04096105) | Celgene | 2019-10-14 |
| Aerosol Particle Size and Breathing Pattern During Inhaled Furosemide (NCT04130815) | Oxford Brookes University | 2019-10-14 |
| HI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Hepatic Impaired Patients and Healthy Subjects (NCT04252417) | MedDay Pharmaceuticals SA | 2019-10-11 |
| Evaluation of Egg Consumption and Its Enrichment With Annatto on Cardiovascular Risk and Satiety in Healthy Adults (NCT05088577) | Universidad de Antioquia | 2019-10-11 |
| RI Study to Assess and Compare the Pharmacokinetic Parameters of MD1003 in Renal Impaired Patients and Healthy Subjects (NCT04252430) | MedDay Pharmaceuticals SA | 2019-10-09 |
| Bioavailability of Enasidenib (CC-90007) Sprinkle Formulation Relative to the Reference Tablet Formulation and Effect of Food on the Pharmacokinetics of Sprinkle Formulation in Healthy Adults (NCT04310527) | Celgene | 2019-10-09 |
| A Research Study of How Oral Semaglutide Tablets Work in Healthy People Who Are Chinese (NCT04016974) | Novo Nordisk A/S | 2019-10-08 |
| A Technical Innovation of Prismatic Adaptation Test in Healthy Subject, in Favour of Autonomy and Independence in Daily Life Following a Brain Injury (NCT03807401) | Hospices Civils de Lyon | 2019-10-08 |
| Drug Interaction Study of the Effect on Cyclosporine on Ozanimod and Major Active Metabolites (NCT04149678) | Celgene | 2019-10-04 |
| Effect Of Hepatic Impairment on the Pharmacokinetics, Safety and Tolerability of PF-06865571 In Subjects With Hepatic Impairment and in Healthy Subjects (NCT04091061) | Pfizer | 2019-10-03 |
| A Study to Evaluate AG-881 in Healthy Japanese and Non-Asian Participants (NCT04145128) | Agios Pharmaceuticals, Inc. | 2019-10-02 |
| A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (C) Semaglutide Tablets (NCT04109508) | Novo Nordisk A/S | 2019-10-02 |
| Study to Assess the Safety, Tolerability, and Pharmacokinetics of BIIB104 in Healthy Japanese and Non-Japanese Participants (NCT04079101) | Biogen | 2019-10-02 |
| Spatial and Dynamic Characterization of Brain Activity for Language and Posture (Verticality) During Normal Aging. Magnetoencephalography (MEG) Study (MEG-AGING) (NCT04036162) | University Hospital, Grenoble | 2019-10-01 |
| Effect of Ghrelin on Decision-Making (NCT03198143) | Jenny Tong, MD, MPH | 2019-10-01 |
| Comparing Pertechnetate SPECT/CT and Intragastric Pressure During Nutrient Drink for Gastric Accommodation (NCT06673719) | Universiti Sains Malaysia | 2019-10-01 |
| Exploring the Effects of Corticosteroids on the Human Hippocampus (NCT03896659) | University of Texas Southwestern Medical Center | 2019-10-01 |
| A Research Study Comparing Active Drug in the Blood in Healthy Participants Following Dosing of the Current and a New Formulation (D) Semaglutide Tablets (NCT04097600) | Novo Nordisk A/S | 2019-09-30 |
| A Study to Compare the Relative Bioavailability of Two AG-881 Formulations and Evaluate the Effect of Food and Omeprazole on the Pharmacokinetics of AG-881 (NCT04128787) | Agios Pharmaceuticals, Inc. | 2019-09-30 |
| Neuroplasticity Induced by General Anaesthesia (NCT04125121) | Signe Sloth Madsen | 2019-09-26 |
| The Role of Dietary Intake and Host Genetics in Gut Microbiome Response to Resistant Starch Consumption (NCT05743790) | Cornell University | 2019-09-26 |
| A Study of PF-06651600 Effect on Rosuvastatin Pharmacokinetics in Healthy Participants (NCT04092595) | Pfizer | 2019-09-26 |
| First-In-Human Study of Apramycin (NCT04105205) | Juvabis AG | 2019-09-25 |
| Pharmacokinetic Study Comparing MB02 And US And EU Avastin® In Healthy Male Volunteers (NCT04238663) | mAbxience Research S.L. | 2019-09-24 |
| Study to Assess the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of ASP1617 in Healthy Adult Non-Asian and Japanese Subjects Including Assessment of a Food Effect (NCT04077879) | Astellas Pharma Global Development, Inc. | 2019-09-19 |
| Cardiovascular Health Arterial Stiffness Raspberry and Microbiome (CHARM) (NCT04087278) | King's College London | 2019-09-19 |
| Phase I Study of D-0120 to Evaluate Safety and PK/PD Study in Healthy Volunteers (NCT04097405) | InventisBio Co., Ltd | 2019-09-18 |
| Mass Balance and Pharmacokinetics of [14C]-CRN00808 in Healthy Volunteers (NCT04246749) | Crinetics Pharmaceuticals Inc. | 2019-09-17 |
| Pharmacokinetics in End Stage Renal Disease Patients (NCT04792333) | Quantum Genomics SA | 2019-09-17 |
| Transfusion of Biotin-Labeled Red Blood Cells (NCT03364686) | Gladwin, Mark, MD | 2019-09-16 |
| Safety and Tolerability, Pharmacokinetic and Pharmacodynamic Study With IZD334 (NCT04086602) | Inflazome UK Ltd | 2019-09-13 |
| Single Ascending Dose Study to Assess the Safety, Tolerability, PK and PD of ONO-4685 in Japanese and Caucasian Healthy Adult Male Subjects (NCT04079062) | Ono Pharmaceutical Co., Ltd. | 2019-09-12 |
| Adaptation of Thirst to a Single Administration of Tolvaptan (TOLVATHIRST) (NCT03931369) | Assistance Publique - Hôpitaux de Paris | 2019-09-06 |
| Study Evaluating Pharmacokinetics and Mass Balance of [14C]-CTP-543 in Healthy Adult Male Volunteers (NCT04092712) | Concert Pharmaceuticals | 2019-09-05 |
| Spire Health Remote Patient Monitor Human Factors Summative Study Protocol (NCT06395350) | Spire, Inc. | 2019-09-04 |
| A Pharmacokinetics and Tolerability Study of Fedratinib in Subjects With Moderate and Severe Hepatic Impairment (NCT03983161) | Celgene | 2019-09-04 |
| Comparison of Explicit, Implicit and no Values Clarification Decision Aids for Men Considering Prostate Cancer Screening (NCT03988673) | Universidade do Porto | 2019-09-01 |
| Evaluation of Kisspeptin Glucose-Stimulated Insulin Secretion With Physiologic Mixed Meal Tolerance (NCT04532801) | Stephanie B. Seminara, MD | 2019-09-01 |
| A Study to Evaluate the Safety, Tolerability Pharmacokinetics, and Pharmacodynamics of a New Spray Dried Dispersion (SDD) Formulation of CC-11050 After Single Dose of CC-11050 and to Evaluate the Pharmacokinetics of CC-11050 Under Fasted and Fed Conditions and After Coadministration With Omeprazole (NCT04139226) | Amgen | 2019-08-28 |
| A Study of RBT-1 in Healthy Volunteers and Subjects With Stage 3/4 Chronic Kidney Disease (NCT03893799) | Renibus Therapeutics, Inc. | 2019-08-27 |
| PET Study of a2a Agonist Effects on the Ventricular CSF Clearance of [11C]Butanol (NCT04032691) | Weill Medical College of Cornell University | 2019-08-27 |
| Effect of Multiple Doses of Modafinil on the Pharmacokinetics of Single Dose Lorlatinib in Healthy Participants (NCT03961997) | Pfizer | 2019-08-22 |