| Improving Understanding of Brain Tumors Through Preservation of Biologically Active Brain Tissue (NCT04545177) | Case Comprehensive Cancer Center | 2020-09-17 |
| In Situ Immune Parameters and Their Prognostic Role on the Survival of Patients With Glioblastoma (NCT03481231) | Centre Georges Francois Leclerc | 2020-09-13 |
| Anlotinib Combined With Dose-dense Temozolomide for the First Recurrent or Progressive Glioblastoma After STUPP Regimen (NCT04547855) | Yonggao Mou | 2020-09-11 |
| Anti-Cancer Effects of Carvedilol With Standard Treatment in Glioblastoma and Response of Peripheral Glioma Circulating Tumor Cells (NCT03980249) | West Virginia University | 2020-09-01 |
| A Trail of Fluzoparil in Combination With Temozolomide in Patients With Recurrent Glioblastoma (NCT04552977) | Shandong Cancer Hospital and Institute | 2020-09-01 |
| DC Migration Study to Evaluate TReg Depletion In GBM Patients With and Without Varlilumab (NCT03688178) | Annick Desjardins, MD | 2020-08-26 |
| VB-111 in Surgically Accessible Recurrent/Progressive GBM (NCT04406272) | Dana-Farber Cancer Institute | 2020-08-01 |
| Physical Training in Glioblastoma Patients During Cytotoxic Therapy (NCT05015543) | University Hospital Muenster | 2020-07-23 |
| Efficacy and Safety of NaviFUS System add-on Bevacizumab (BEV) in Recurrent GBM Patients (NCT04446416) | NaviFUS Corporation | 2020-07-21 |
| Infigratinib in Recurrent High-Grade Glioma Patients (NCT04424966) | Nader Sanai | 2020-07-21 |
| Neoantigen-based Personalized DNA Vaccine in Patients With Newly Diagnosed, Unmethylated Glioblastoma (NCT04015700) | Washington University School of Medicine | 2020-07-14 |
| LY3214996 Plus Abemaciclib in Recurrent Glioblastoma Patients (NCT04391595) | Nader Sanai | 2020-07-11 |
| A Study of CC-90010 in Combination With Temozolomide With or Without Radiation Therapy in Participants With Newly Diagnosed Glioblastoma (NCT04324840) | Celgene | 2020-07-10 |
| Clindamycin and Triamcinolone in People With Glioblastoma to Prevent Skin-Related Side Effects of Tumor Treating Fields (NCT04469075) | Memorial Sloan Kettering Cancer Center | 2020-07-09 |
| Selinexor (KPT-330) in Combination With Temozolomide and Radiation Therapy in Patients With Newly Diagnosed Glioblastoma (NCT04216329) | National Cancer Institute (NCI) | 2020-07-07 |
| A Phase 1-2 Study of ST101 in Patients With Advanced Solid Tumors (NCT04478279) | Sapience Therapeutics | 2020-07-01 |
| Supramarginal Resection in Glioblastoma (NCT04243005) | St. Olavs Hospital | 2020-07-01 |
| Evaluation of Maximum Tolerated Dose, Safety and Efficiency of MSC11FCD Therapy to Recurrent Glioblastoma Patients (NCT04657315) | CHA University | 2020-06-24 |
| Anti-GITR/Anti-PD1/Stereotactic Radiosurgery, in Recurrent Glioblastoma (NCT04225039) | University of Pennsylvania | 2020-06-23 |
| Anticancer Therapeutic Vaccination Using Telomerase-derived Universal Cancer Peptides in Glioblastoma (NCT04280848) | Centre Hospitalier Universitaire de Besancon | 2020-05-26 |
| The Efficacy and Safety of Brain-targeting Immune Cells (EGFRvIII-CAR T Cells) in Treating Patients With Leptomeningeal Disease From Glioblastoma. Administering Patients EGFRvIII -CAR T Cells May Help to Recognize and Destroy Brain Tumor Cells in Patients (NCT05063682) | Chembrain LTD | 2020-05-15 |
| Restrictive Use of Dexamethasone in Glioblastoma (NCT04266977) | Insel Gruppe AG, University Hospital Bern | 2020-05-08 |
| Retifanlimab and Epacadostat in Combination With Radiation and Bevacizumab in Patients With Recurrent Gliomas (NCT03532295) | Washington University School of Medicine | 2020-04-20 |
| Tumor Electric Fields Treatment System for Glioblastoma (NCT04417933) | Xiangya Hospital of Central South University | 2020-04-07 |
| Neoadjuvant Chemoradiation for Resectable Glioblastoma (NCT04209790) | Geisinger Clinic | 2020-04-01 |
| NKG2D-based CAR T-cells Immunotherapy for Patient With r/r NKG2DL+ Solid Tumors (NCT04270461) | Jiujiang University Affiliated Hospital | 2020-03-17 |
| FDG and FDOPA PET Demonstration of Functional Brain Abnormalities (NCT04315584) | University of Virginia | 2020-03-15 |
| Implantable Microdevice In Primary Brain Tumors (NCT04135807) | Oliver Jonas | 2020-03-03 |
| Sulfasalazine and Stereotactic Radiosurgery for Recurrent Glioblastoma (NCT04205357) | Haukeland University Hospital | 2020-03-01 |
| 18F-FluorThanatrace (PET/CT) in Glioblastoma (NCT04221061) | University of Pennsylvania | 2020-02-20 |
| Dabrafenib Combined With Trametinib After Radiation Therapy in Treating Patients With Newly-Diagnosed High-Grade Glioma (NCT03919071) | National Cancer Institute (NCI) | 2020-02-20 |
| Study of Laser Interstitial Thermal Therapy (LITT) Treatment Response Assessment With Fluciclovine PET MR (NCT05054400) | M.D. Anderson Cancer Center | 2020-02-05 |
| Testing the Addition of an Anti-cancer Viral Gene Therapy, Toca 511/Toca FC, to the Usual Treatment (Temozolomide and Radiation Therapy) for Newly Diagnosed Glioblastoma (NCT04105374) | NRG Oncology | 2020-01-31 |
| Chemotherapy and Radiation Therapy for the Treatment of IDH Wildtype Gliomas or Non-histological (Molecular) Glioblastomas (NCT04623931) | M.D. Anderson Cancer Center | 2020-01-30 |
| Serial MRI Scans During Radiation Therapy (NCT04188535) | Dana-Farber Cancer Institute | 2020-01-15 |
| LITT Followed by Hypofractionated RT for Recurrent Gliomas (NCT04181684) | University of Maryland, Baltimore | 2020-01-08 |
| Laparoscopically Harvested Omental Free Tissue Autograft to Bypass the Blood Brain Barrier (BBB) in Human Recurrent Glioblastoma Multiforme (rGBM) (NCT04222309) | Northwell Health | 2020-01-06 |
| CNS Penetration, PK and PD of Preoperative CC-90010 in Progressive/Recurrent Diffuse Astrocytoma, Anaplastic Astrocytoma and Glioblastoma (NCT04047303) | Celgene | 2020-01-02 |
| Addition of Anlotinib Hydrochloride to the Stupp Regimen Versus the Stupp Regimen Alone for Newly Diagnosed Glioblastoma (NCT04157478) | People's Hospital of Guangxi Zhuang Autonomous Region | 2020-01-01 |
| Feasibility of Intra- and Post-operative Microdialysis During Neurosurgery for Central Nervous System Lesions (NCT04047264) | Mayo Clinic | 2020-01-01 |
| Niraparib/TTFields in GBM (NCT04221503) | Abramson Cancer Center at Penn Medicine | 2019-12-30 |
| Abemaciclib w/Bevacizumab in Recurrent GBM Pts w/Loss of CDKN2A/B or Gain or Amplification of CDK4/6 (NCT04074785) | University of Texas Southwestern Medical Center | 2019-12-13 |
| Determining Dose of Regadenoson Most Likely to Transiently Alter the Integrity of the Blood-Brain Barrier in Patients With High Grade Gliomas (NCT03971734) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2019-12-06 |
| Tumor Treating Fields With Chemoradiation in Newly Diagnosed GBM (NCT03705351) | Providence Health & Services | 2019-12-02 |
| Pediatric Long-Term Follow-up and Rollover Study (NCT03975829) | Novartis Pharmaceuticals | 2019-11-04 |
| Bioenergetic Profiling and Cognition in GBM Patients (NCT03939858) | Wake Forest University Health Sciences | 2019-10-24 |
| Pediatric Trial of Indoximod With Chemotherapy and Radiation for Relapsed Brain Tumors or Newly Diagnosed DIPG (NCT04049669) | Theodore S. Johnson | 2019-10-02 |
| Imaging Perfusion Restrictions From Extracellular Solid Stress - An Open-label Losartan Study (NCT03951142) | Kyrre Eeg Emblem | 2019-10-01 |
| Immunotherapy Targeted Against Cytomegalovirus in Patients With Newly-Diagnosed WHO Grade IV Unmethylated Glioma (NCT03927222) | Mustafa Khasraw, MBChB, MD, FRCP, FRACP | 2019-09-30 |
| Glioblastoma Treatment With Irradiation and Olaptesed Pegol (NOX-A12) in MGMT Unmethylated Patients (NCT04121455) | TME Pharma AG | 2019-09-12 |
| Antisecretory Factor in Primary Glioblastoma 1 (NCT04116138) | Peter Siesjö | 2019-09-01 |
| Nivolumab, BMS-986205, and Radiation Therapy With or Without Temozolomide in Treating Patients With Newly Diagnosed Glioblastoma (NCT04047706) | Northwestern University | 2019-08-13 |
| Study of Ad-RTS-hIL-12 + Veledimex in Combination With Cemiplimab in Subjects With Recurrent or Progressive Glioblastoma (NCT04006119) | Alaunos Therapeutics | 2019-08-01 |
| A Trial to Evaluate Multiple Regimens in Newly Diagnosed and Recurrent Glioblastoma (NCT03970447) | Global Coalition for Adaptive Research | 2019-07-30 |
| Study of Binimetinib With Encorafenib in Adults With Recurrent BRAF V600-Mutated HGG (NCT03973918) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2019-07-29 |
| Carvedilol With Chemotherapy in Second Line Glioblastoma and Response of Circulating Tumor Cells (NCT03861598) | West Virginia University | 2019-07-19 |
| Neuro/Sacituzumab Govitecan/Breast Brain Metastasis/Glioblastoma/Ph 0 (NCT03995706) | The University of Texas Health Science Center at San Antonio | 2019-07-17 |
| A Explorative Study to Evaluate the Clinical Feasibility of AVATAMED (NCT04313842) | Doo-Sik Kong | 2019-07-01 |
| Study of Prognostic Biomarkers of Survival at 6 Months for Patients Treated With Bevacizumab Glioblastomas in First Relapse After Failure of Radiochemotherapy (NCT03144167) | Centre Hospitalier Universitaire, Amiens | 2019-06-18 |
| Customized Neuro-Imaging Referenced Symptom Video for the Reduction of Patient and Caregiver Anxiety Around Radiation Treatment for Brain Tumors (NCT04479696) | M.D. Anderson Cancer Center | 2019-06-05 |
| A Study of the Safety and Pharmacokinetics of BRCX014 in Patients With Glioblastoma (NCT03687034) | Leaf Vertical Inc. | 2019-06-01 |
| LITT Palliative Treatment for Patients With Malignant Gliomas (NCT03176160) | Duke University | 2019-06-01 |
| Biologically-based Target Volumes to Treat Newly Diagnosed Glioblastoma (NCT03506139) | John M. Buatti | 2019-05-15 |
| Memory Perception Assessment in Central/Non-central Nervous System Cancers (NCT03975959) | Institut du Cancer de Montpellier - Val d'Aurelle | 2019-05-10 |
| Precoce Medical Care by the Mobil Support for Patients With Glioblastoma (NCT04516733) | Institut du Cancer de Montpellier - Val d'Aurelle | 2019-05-10 |
| Feasibility of the LUM Imaging System for Detection of Cancer to the Brain (NCT03717142) | Lumicell, Inc. | 2019-05-03 |
| F18 Fluciclovine PET/CT in Assessing Tumor Volume and Radiation Therapy Response in Patients With Glioblastoma Undergoing Surgery (NCT03926507) | M.D. Anderson Cancer Center | 2019-04-30 |
| Differentiation Between Healthy Cerebral Tissue and Tumor Tissue Using a Tissue Sensing Instrument (NCT05171127) | Karolinska University Hospital | 2019-04-30 |
| Non-Contrast Perfusion Using Arterial Spin Labeled MR Imaging for Assessment of Therapy Response in Glioblastoma (NCT03922984) | University of Texas Southwestern Medical Center | 2019-04-16 |
| BGB-290 and Temozolomide in Treating Isocitrate Dehydrogenase (IDH)1/2-Mutant Grade I-IV Gliomas (NCT03749187) | University of California, San Francisco | 2019-04-03 |
| The SAFE-Trial: Awake Craniotomy Versus Surgery Under General Anesthesia for Glioblastoma Patients. (NCT03861299) | Jasper Gerritsen | 2019-04-01 |
| 18F-DOPA-PET/MRI Scan in Imaging Elderly Patients With Newly Diagnosed Grade IV Malignant Glioma or Glioblastoma During Planning for a Short Course of Proton Beam Radiation Therapy (NCT03778294) | Mayo Clinic | 2019-03-28 |
| Nivolumab in Patients With IDH-Mutant Gliomas With and Without Hypermutator Phenotype (NCT03718767) | National Cancer Institute (NCI) | 2019-03-27 |
| Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption (NCT03551249) | InSightec | 2019-03-26 |
| Testing Ramipril to Prevent Memory Loss in People With Glioblastoma (NCT03475186) | Wake Forest University Health Sciences | 2019-03-25 |
| Biomarker-Driven Therapy Using Immune Activators With Nivolumab in Patients With First Recurrence of Glioblastoma (NCT03707457) | Sidney Kimmel Comprehensive Cancer Center at Johns Hopkins | 2019-03-22 |
| Improving Treatment of Glioblastoma: Distinguishing Progression From Pseudoprogression (NCT04359745) | Guy's and St Thomas' NHS Foundation Trust | 2019-03-21 |
| Treatment Intensification With Temozolomide in Adults With a Glioblastoma (NCT03663725) | Centre Oscar Lambret | 2019-03-13 |
| CART-EGFRvIII + Pembrolizumab in GBM (NCT03726515) | University of Pennsylvania | 2019-03-11 |
| Early Diagnosis of Pseudoprogression Using 11C-Methionine PET-MRI After Concomitant Radiochemotherapy Treatment for Glioblastoma. (NCT03739333) | Hospices Civils de Lyon | 2019-02-26 |
| Efficacy and Safety of Pembrolizumab (MK-3475) Plus Lenvatinib (E7080/MK-7902) in Previously Treated Participants With Select Solid Tumors (MK-7902-005/E7080-G000-224/LEAP-005) (NCT03797326) | Merck Sharp & Dohme LLC | 2019-02-12 |
| Olaparib in Treating Patients With Advanced Glioma, Cholangiocarcinoma, or Solid Tumors With IDH1 or IDH2 Mutations (NCT03212274) | National Cancer Institute (NCI) | 2019-01-30 |
| A Phase 1 Study of ZSP1602 in Participants With Advanced Solid Tumors (NCT03734913) | Guangdong Zhongsheng Pharmaceutical Co., Ltd. | 2019-01-25 |
| Phase I Study of Monoclonal Antibondy (GS) 5745, an Matix Metalloproteinase 9 (MMP9) Mab Inhibitor, in Combination With Bevacizumab in Patients With Recurrent Glioblastoma (NCT03631836) | Assistance Publique Hopitaux De Marseille | 2019-01-01 |
| Study to Evaluate Ibudilast and TMZ Combo Treatment in Newly Diagnosed and Recurrent Glioblastoma (NCT03782415) | MediciNova | 2018-12-29 |
| Study of Stereotactic Radiosurgery to the Subventricular Zone in Malignant Gliomas (NCT03956706) | Northwell Health | 2018-12-24 |
| Whole Brain Radiation Therapy With Standard Temozolomide Chemo-Radiotherapy and Plerixafor in Treating Patients With Glioblastoma (NCT03746080) | Lawrence D Recht | 2018-12-04 |
| Predictive Value of Progastrin Titer at Diagnosis and of Progastrin Kinetics During Treatment in Cancer Patients (NCT03787056) | Hospices Civils de Lyon | 2018-12-04 |
| Grafts of GSCs Into Brain Organoids for Testing Anti-invasion Drugs (NCT05772741) | Fondazione Policlinico Universitario Agostino Gemelli IRCCS | 2018-12-03 |
| Clinical Benefit of Using Molecular Profiling to Determine an Individualized Treatment Plan for Patients With High Grade Glioma (NCT03739372) | University of California, San Francisco | 2018-11-28 |
| 18F-FDG PET and Osimertinib in Evaluating Glucose Utilization in Patients with EGFR Activated Recurrent Glioblastoma (NCT03732352) | Jonsson Comprehensive Cancer Center | 2018-11-28 |
| Doxorubicin-loaded Anti-EGFR-immunoliposomes (C225-ILs-dox) in High-grade Gliomas (NCT03603379) | University Hospital, Basel, Switzerland | 2018-11-16 |
| Nivolumab With Radiation Therapy and Bevacizumab for Recurrent MGMT Methylated Glioblastoma (NCT03743662) | Memorial Sloan Kettering Cancer Center | 2018-11-12 |
| Veliparib, Radiation Therapy, and Temozolomide in Treating Patients With Newly Diagnosed Malignant Glioma Without H3 K27M or BRAFV600 Mutations (NCT03581292) | National Cancer Institute (NCI) | 2018-11-06 |
| Neoantigen-based Personalized Vaccine Combined With Immune Checkpoint Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma (NCT03422094) | Washington University School of Medicine | 2018-10-31 |
| DNX-2440 Oncolytic Adenovirus for Recurrent Glioblastoma (NCT03714334) | Clinica Universidad de Navarra, Universidad de Navarra | 2018-10-16 |
| Assessment of Safety and Feasibility of ExAblate Blood-Brain Barrier (BBB) Disruption for Treatment of Glioma (NCT03616860) | InSightec | 2018-10-16 |
| Phase II/III Trial of CCRT With or Without JP001 for Newly Diagnosed GBM (NCT03008148) | Johnpro Biotech, Inc. | 2018-10-11 |
| A Study of PLB1001 Enteric Capsules in the Treatment of sGBM/IDH Mutant Glioblastoma Patients With the ZM Fusion Gene (FUGEN). (NCT06105619) | Beijing Pearl Biotechnology Limited Liability Company | 2018-10-08 |
| Cytomegalovirus (CMV) RNA-Pulsed Dendritic Cells for Pediatric Patients and Young Adults With WHO Grade IV Glioma, Recurrent Malignant Glioma, or Recurrent Medulloblastoma (NCT03615404) | Gary Archer Ph.D. | 2018-10-05 |