| Phase 2A Open Label Safety Study of Fovista® (Anti-PDGF BB) Regimen Administered in Combination With Anti-VEGF Therapy to Study Sub-Retinal Fibrosis in Neovascular AMD (NCT02214628) | Ophthotech Corporation | 2014-07-01 |
| A Pharmacokinetic Study: Ranibizumab, Aflibercept and the Effect of Vitrectomy. (NCT02174211) | King's College Hospital NHS Trust | 2014-06-01 |
| Ziv-aflibercept in Eyes With Retinal Diseases and Poor Vision-phase I (NCT02173873) | Rafic Hariri University Hospital | 2014-06-01 |
| Resistance to Antibiotics in Patients Receiving Eye Injections (NCT02126423) | Prism Vision Group | 2014-05-01 |
| Intravitreal Aflibercept in Wet Age Related Macular Degeneration Patients With an Incomplete Response to Routine Ranibizumab Injections (NCT02002377) | Unity Health Toronto | 2014-04-17 |
| A Comparison of Ranibizumab and Aflibercept for the Development of Geographic Atrophy in (Wet) AMD Patients (NCT02130024) | Novartis Pharmaceuticals | 2014-04-11 |
| Phase 1 Safety Study of ALK-001 in Healthy Volunteers (NCT02230228) | Alkeus Pharmaceuticals, Inc. | 2014-04-01 |
| Brain Connectivity in Age-Related Macular Degeneration (NCT01996215) | Duke University | 2014-04-01 |
| Long-Term Follow-up Safety Study of Human Central Nervous System Stem Cells in Subjects With Geographic Atrophy of Age-Related Macular Degeneration (NCT02137915) | StemCells, Inc. | 2014-04-01 |
| Pharmacokinetic and Pharmacodynamic Study of Emixustat in Subjects With Geographic Atrophy Associated With Dry Age-Related Macular Degeneration (NCT02130531) | Kubota Vision Inc. | 2014-04-01 |
| First-in-Human Study of LHA510 in Elderly Subjects and Patients With Age-Related Macular Degeneration (NCT02076919) | Alcon Research | 2014-02-01 |
| A Phase I/II Safety Study of DE-120 Injectable Solution for Age-related Macular Degeneration (NCT02022501) | Santen Inc. | 2014-01-01 |
| Randomized Study for Efficacy and Safety of Ranibizumab 0.5mg in Treat-extend and Monthly Regimens in Patients With nAMD (NCT01948830) | Novartis Pharmaceuticals | 2013-12-17 |
| Visual Outcome in Patients With Symptomatic Macular Polypoidal Choroidal Vasculopathy (PCV) Treated With Either Ranibizumab as Monotherapy or Combined With Verteporfin Photodynamic Therapy (vPDT) (NCT01846273) | Novartis Pharmaceuticals | 2013-08-07 |
| Genetic Biomarkers for the Response to Anti-VEGF (Vascular Endothelial Growth Factor).Treatment in Wet Age-related Macular Degeneration (Wet ARMD) (NCT02762188) | Brugmann University Hospital | 2013-08-01 |
| A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy (NCT01944839) | Ophthotech Corporation | 2013-08-01 |
| A Phase 3 Safety and Efficacy Study of Fovista® (E10030) Intravitreous Administration in Combination With Lucentis® Compared to Lucentis® Monotherapy (NCT01940900) | Ophthotech Corporation | 2013-08-01 |
| Study of the Effects of Supplements on Eye Disease in Participants From the Age-Related Eye Disease Study (NCT01915238) | National Eye Institute (NEI) | 2013-07-16 |
| High Resolution Retinal Imaging (NCT01866371) | University of Pennsylvania | 2013-05-01 |
| Proton Radiation Therapy for Macular Degeneration (NCT01833325) | University of Florida | 2013-05-01 |
| Pharmacokinetics of CLG561 in Patients With Advanced Age-Related Macular Degeneration (NCT01835015) | Alcon Research | 2013-05-01 |
| Evaluation of TeleOphthalmology in AMD-TeleMedicine Solutions to Improve Patient Access and Quality of Vision Outcomes (NCT01581606) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2013-04-30 |
| Safety Study of Use of Autologous Bone Marrow Derived Stem Cell in Treatment of Age Related Macular Degeneration (NCT02016508) | Al-Azhar University | 2013-03-01 |
| Efficacy of Acupuncture in Macular Diseases (NCT02255981) | Escuela Neijing | 2013-03-01 |
| Study of PRN and Every 2months Intravitreal Aflibercept for Age Related Macular Degeneration (NCT01824225) | Nihon University | 2013-03-01 |
| Mobile Clinic - a Cross-sectional Epidemiological Survey (NCT02055612) | Novartis Slovakia, s.r.o. | 2013-03-01 |
| Effects of Sildenafil on Choroidal Thickness in AMD (NCT01830790) | Duke University | 2013-03-01 |
| Comparison of Phase-variance Optical Coherence Tomography and Fluorescein Angiography in Retinovascular Imaging (NCT01717937) | University of California, San Francisco | 2013-02-01 |
| Ranibizumab In Pigment Epithelium Tears Secondary To Age-Related Macular Degeneration Study (NCT01914159) | University Hospital, Bonn | 2013-02-01 |
| Living Successfully With Chronic Eye Diseases (NCT01879501) | Singapore Eye Research Institute | 2013-01-01 |
| AMD Phenotype and Genotype Study (NCT01778491) | National Eye Institute (NEI) | 2012-11-05 |
| Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration (NCT01731964) | VisionCare, Inc. | 2012-11-01 |
| Genetic Analysis of Chronic Central Serous Chorioretinopathy Masquerading as Neovascular AMD (NCT01880788) | Sequenom, Inc. | 2012-11-01 |
| Association of Previously Verified Gene Polymorphisms With AMD in Turkish Population (NCT02248324) | Kocatepe University | 2012-11-01 |
| Short-term Clinical Effects of Intravitreal Aflibercept Injection 2.0mg as a Predictor of Long-term Results (NCT01657669) | Retina Research Institute, LLC | 2012-10-01 |
| Evaluation of the Precision of the Microperimetry Function of the Spectral OCT/SLO (NCT01692938) | Optos, PLC | 2012-10-01 |
| A Follow-up Study to Evaluate the Safety of RetinoStat® in Patients With Age-Related Macular Degeneration (NCT01678872) | Oxford BioMedica | 2012-08-01 |
| Association of Macular Pigment Optical Density (MPOD) and Genetic Variants in Complement Factor H in Subjects With Choroidal Neovascular (CNV) (NCT01682382) | Sequenom, Inc. | 2012-08-01 |
| Iray for Vascularized Pigment Epithelial Detachment (VPED) Secondary to Age Related Macular Degeneration (NCT01521819) | Oraya Therapeutics, Inc. | 2012-08-01 |
| Micropulse Laser for Geographic Atrophy (NCT01799564) | Institut de la Macula y la Retina | 2012-08-01 |
| On-label tReatment With Intravitreal Aflibercept injectiOn for Patients With Persistent Pigment epitheliaL Detachments in Neovascular Age Related Macular Degeneration (AMD) (NCT01670162) | Tennessee Retina | 2012-08-01 |
| Genetic Load and Phenotype in Aggressive AMD (NCT01650948) | Sequenom, Inc. | 2012-07-01 |
| Evaluation of the Association Between Genetic Load and Response to Anti-VEGF Therapy in AMD Patients (NCT01644513) | Sequenom, Inc. | 2012-07-01 |
| Anesthesia Preference for Intravitreal Injection: Topical or Subconjunctival (NCT01640171) | Retina Vitreous Associates of Florida | 2012-07-01 |
| National Eye Institute Biorepository for Retinal Diseases (NCT01496625) | National Eye Institute (NEI) | 2012-06-18 |
| Study of Human Central Nervous System Stem Cells (HuCNS-SC) in Age-Related Macular Degeneration (AMD) (NCT01632527) | StemCells, Inc. | 2012-06-01 |
| Effect of Intravitreal Anti-VEGF on Retinal Vessels Diameter (NCT01626339) | University of Malaya | 2012-04-01 |
| Omega 6:Omega 3 Ratio and Progression of Age-related Macular Degeneration (AMD). (NCT00987129) | Yves Sauve | 2012-03-01 |
| Systemic Pharmacokinetics Following Intravitreal Injections of Anti-VEGF (NCT02118831) | California Retina Consultants | 2012-03-01 |
| Prospective Study Phase: Retinal Oxygen Saturation, Blood Flow, Vascular Function and High Resolution Morphometric Imaging in the Living Human Eye (NCT01348672) | University of Toronto | 2012-03-01 |
| Blood and Saliva Sample Collection for AREDS 2 (NCT01553474) | National Eye Institute (NEI) | 2012-02-24 |
| Study for Recalcitrant Age Related Macular Degeneration (NCT01543568) | David M. Brown, M.D. | 2012-02-01 |
| Intravitreal LFG316 in Patients With Age-related Macular Degeneration (AMD) (NCT01527500) | Novartis Pharmaceuticals | 2012-01-25 |
| IRay to Treat Polypoidal Choroidal Vasculopathy (PCV) Secondary to Age-Related Macular Degeneration (AMD (NCT01516294) | Oraya Therapeutics, Inc. | 2012-01-01 |
| Plaqenil Role in Prevention of Age Related Macular Degeneration (NCT01541449) | Ziv Hospital | 2012-01-01 |
| Association Between Light Spectrum and Survival After Cataract Surgery (NCT04187157) | University of Pittsburgh | 2012-01-01 |
| Evaluation of Wet Age-Related Macular Degeneration (AMD) Genetic Profile Interactions With Ranibizumab Treatment Outcomes (NCT01363570) | McMaster University | 2012-01-01 |
| Wet AMD Recurrence Rate in Patients Stable on Three Month Ranibizumab Dosing (NCT01453920) | University Health Network, Toronto | 2011-11-01 |
| Laser Intervention in Early Age-Related Macular Degeneration Study (NCT01790802) | Center for Eye Research Australia | 2011-11-01 |
| Treatment of Diabetic Macular Edema With 0.5mg Intraocular Ranibizumab (Lucentis) (NCT01638858) | University of Luebeck | 2011-10-01 |
| Consumption of Eggs Rich in Lutein and Omega-3 Fatty Acids on the Macular Pigment (NCT01480700) | Institut Pasteur de Lille | 2011-10-01 |
| Genetic Polymorphisms in Ranibizumab Treatment in Wet Age-Related Macular Degeneration (AMD) (NCT01676506) | Russian Academy of Medical Sciences | 2011-10-01 |
| Evaluation of AGN-150998 in Exudative Age-related Macular Degeneration (AMD) (NCT01397409) | Allergan | 2011-09-01 |
| Sirolimus for Advanced Age-Related Macular Degeneration (NCT01445548) | National Eye Institute (NEI) | 2011-09-01 |
| A Research Study to Evaluate the Effects of Repeated Intravitreal Injections on Bacteria Around the Eye (NCT01531842) | Mid Atlantic Retina | 2011-08-01 |
| Clinical Assessment Of Age-related Macular Degeneration Patients After Early Diagnosis and Treatment With Ranibizumab (NCT01402544) | University of California, San Diego | 2011-07-01 |
| Study to Evaluate the Safety and Effectiveness of IRay in Wet Age-related Macular Degeneration (AMD) Patients With Recurrent Leakage Secondary to Choroidal Neovascularisation (CNV) (NCT01339949) | Oraya Therapeutics, Inc. | 2011-06-01 |
| SD-OCT-guided Intravitreal Ranibizumab Treatment in Choroidal Neovascularization Due to Myopia (NCT03409250) | Vista Klinik | 2011-06-01 |
| Study of Dark Adaptation in Age-Related Macular Degeneration (NCT01352975) | National Eye Institute (NEI) | 2011-05-16 |
| Study of WA-NG Telescope Prosthesis in Patients With End-stage Age-related Macular Degeneration (NCT01361256) | VisionCare, Inc. | 2011-05-01 |
| Home Vision Monitoring Using the ForeseeHome Device Following Treatment of Neovascular Age Related Macular Degeneration (NCT01334294) | Notal Vision Ltd. | 2011-04-01 |
| Intravitreal Bevacizumab for Low Vision in Neovascular Age-related Macular Degeneration (AMD) (NCT01327222) | IRCCS San Raffaele | 2011-02-01 |
| Phase I Dose Escalation Safety Study of RetinoStat in Advanced Age-Related Macular Degeneration (AMD) (NCT01301443) | Oxford BioMedica | 2011-02-01 |
| Safety and Preliminary Efficacy Study of PDS-1.0 in Patients With Neovascular AMD (NCT01177644) | Forsight Vision4 | 2011-01-01 |
| Cirrus HD-OCT Measurement of Area of Increased Light Penetration Under the Retinal Pigment Epithelium (RPE) (NCT01272076) | Carl Zeiss Meditec, Inc. | 2011-01-01 |
| Palomid 529 in Patients With Neovascular Age-Related Macular Degeneration (NCT01271270) | National Eye Institute (NEI) | 2010-12-20 |
| Seven Year Update of Macular Degeneration Patients (NCT01256827) | University of California, San Francisco | 2010-12-01 |
| Time Course of Activity Signs at SD-OCT High Frequency Intravitreal Ranibizumab Treatment in CNV Due to AMD (NCT03393767) | Vista Klinik | 2010-12-01 |
| Determining the Effect of Antibiotic Drop Prophylaxis on the Conjunctival Flora (NCT01577342) | London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's | 2010-11-01 |
| A Safety Study of CNTO 2476 in Patients With Age-Related Macular Degeneration (NCT01226628) | Janssen Research & Development, LLC | 2010-10-21 |
| LOC387715/HTRA1 and the Combined Photodynamic Therapy With Intravitreal Bevacizumab in Polypoidal Choroidal Vasculopathy (NCT01233115) | Kyungpook National University Hospital | 2010-10-01 |
| Ranibizumab Short- and Log-term Effects on Retinal Function in wAMD (NCT01269151) | University of Luebeck | 2010-10-01 |
| Retinal Imaging by Adaptive Optics in Healthy Eyes and During Retinal and General Diseases (NCT01546181) | Institut National de la Santé Et de la Recherche Médicale, France | 2010-10-01 |
| Vascular Endothelial Growth Factor (VEGF) & LOC387715/HTRA1 Polymorphism in Polypoidal Choroidal Vasculopathy (NCT01233128) | Kyungpook National University Hospital | 2010-10-01 |
| 20089 TA+Lucentis Combo Intravitreal Injections for Treatment of Neovascular Age-related Macular Degeneration (AMD) (NCT01175395) | University of Illinois at Chicago | 2010-09-01 |
| Preliminary Safety and Efficacy of the PDS-1.0 in Patients With Neovascular Age Related Macular Degeneration (AMD) (NCT01186432) | Forsight Vision4 | 2010-08-01 |
| Retinal Therapy Guided by 3D OCT Image Analysis (NCT02308215) | Michael Abramoff | 2010-07-01 |
| Age-related Macular Degeneration (AMD) in the Vitamin D and Omega-3 Trial (VITAL) (NCT01782352) | Brigham and Women's Hospital | 2010-07-01 |
| Selective Retinal Pigment Epithelium Laser Therapy for Macular Disease of the Retina (NCT02088151) | Insel Gruppe AG, University Hospital Bern | 2010-06-01 |
| WALTZ - Wet Age-Related Macular Degeneration (AMD) AL-39324 Treatment Examination (NCT00992563) | Alcon Research | 2010-06-01 |
| Ranibizumab and the Risk of Arterial Thromboembolic Events (NCT01319188) | Ural State Medical University | 2010-06-01 |
| Phase I Study of Palomid 529 a Dual TORC1/2 Inhibitor of the PI3K/Akt/mTOR Pathway for Advanced Neovascular Age-Related Macular Degeneration (NCT01033721) | Paloma Pharmaceuticals, Inc. | 2010-06-01 |
| Effects of Xanthophylls on Optical Density (NCT01316198) | University of Jena | 2010-06-01 |
| Effects of Lutein and Zeaxanthin Supplementation on Early Age-related Macular Degeneration (NCT01528605) | Peking University | 2010-06-01 |
| A Pilot Study to Evaluate the Role of High-dose Ranibizumab (2.0mg) in the Management of AMD in Patients With Persistent/Recurrent Macular Fluid Less Than 30 Days Following Treatment With Intravitreal Anti-VEGF Therapy (the LAST Study) (NCT01115556) | Vitreous -Retina- Macula Consultants of New York | 2010-05-01 |
| HOme Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome Device (NCT01103505) | Notal Vision Ltd. | 2010-05-01 |
| Intravitreal Adalimumab in Patients With Choroidal Neovascularization Secondary to Age-related Macular Degeneration (NCT01136252) | Hospital Universitari Vall d'Hebron Research Institute | 2010-05-01 |
| Tools to Optimize Patient Presentation After Onset of Exudative Age-Related Macular Degeneration (AMD) (NCT01337414) | Johns Hopkins University | 2010-05-01 |
| Extension Study to Gather Data on Effect of Macugen on the Corneal Endothelium (NCT01573572) | Bausch & Lomb Incorporated | 2010-04-22 |
| LOC387715/HTRA1 Variants in Polypoidal Choroidal Vasculopathy in a Korean Population (NCT01108250) | Kyungpook National University Hospital | 2010-04-01 |