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SIR-SPHERES MICROSPHERES

FDA premarket approval P990065/S010 · decided 2017-01-18

Approval details

PMA number
P990065
Supplement
S010
Supplement type
Special (Immediate Track)
Supplement reason
Process Change - Manufacturer/Sterilizer/Packager/Supplier
Trade name
SIR-SPHERES MICROSPHERES
Generic name
Microspheres radionuclide
Applicant
Sirtex Medical, Inc.
Date received
2016-12-19
Decision date
2017-01-18
Days to decision
30 days
Decision code
APPR
Product code
NAW
Advisory committee
Radiology
Expedited review
No
Location
Woburn, MA
Statement
Approval for changes in device package insert with insertion of BSA model to replace the current empirical model for calculation of individual required activity dose, change of lung shunt fraction to total lung dose, less than 30 Gy to apply in the dose calculation, re-define the Radio-Embolization Induced Liver Disease (REILD) and addition of dose reduction guidance in REILD, addition of guidance of lobar therapy using BSA model, and deletion of empirical model and partition model for dose calc

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