Atlas FDA

Restylane Refyne, Restylane Defyne

FDA premarket approval P140029/S019 · decided 2019-09-30

Approval details

PMA number
P140029
Supplement
S019
Supplement type
Real-Time Process
Supplement reason
Change Design/Components/Specifications/Material
Trade name
Restylane Refyne, Restylane Defyne
Generic name
Implant, dermal, for aesthetic use
Applicant
Q-Med AB
Date received
2019-07-02
Decision date
2019-09-30
Days to decision
90 days
Decision code
APPR
Product code
LMH
Advisory committee
General, Plastic Surgery
Expedited review
No
Location
Uppsala
Statement
Approval for the removal of testing of heavy metals in raw materials as per USP<231> and replacing it by a risk analysis on the final product based on ICH Q3D guideline for Elemental Impurities for Restylane Refyne and Restylane Defyne.

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