Atlas FDA

Proliv™Rx System

FDA premarket approval P250010 · decided 2025-12-31

Approval details

PMA number
P250010
Trade name
Proliv™Rx System
Generic name
Cranial electrotherapy stimulator to treat depression
Applicant
Neurolief , Ltd.
Date received
2025-03-26
Decision date
2025-12-31
Days to decision
280 days
Decision code
APPR
Product code
JXK
Advisory committee
Neurology
Expedited review
No
Location
Netanya
Statement
The Proliv™Rx System provides focal external Combined Occipital and Trigeminal Afferent Stimulation (eCOT-AS) treatment. It is intended as an adjunctive treatment for Major Depressive Disorder (MDD) in adults who failed to achieve satisfactory improvement from at least one previous antidepressant medication, for use at home or in clinic. It is a prescription-only device.

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510(k) clearances by this applicant

RecordFirmDate
Relivion (K212106)Neurolief , Ltd.2021-08-02
Relivion (K203419)Neurolief , Ltd.2021-02-16