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PearlMatrix™ P-15 Peptide Enhanced Bone Graft (PearlMatrix™ Bone Graft)

FDA premarket approval P240001/S001 · decided 2025-12-11

Approval details

PMA number
P240001
Supplement
S001
Supplement type
Normal 180 Day Track
Supplement reason
Labeling Change - Indications/instructions/shelf life/tradename
Trade name
PearlMatrix™ P-15 Peptide Enhanced Bone Graft (PearlMatrix™ Bone Graft)
Generic name
Filler, bone void, synthetic peptide
Applicant
Cerapedics, Inc.
Date received
2025-09-08
Decision date
2025-12-11
Days to decision
94 days
Decision code
APPR
Product code
NOX
Advisory committee
Orthopedic
Expedited review
No
Location
Westminster, CO
Statement
Approval to allow implantation of the product using additional open or minimally invasive surgical approaches: ALIF (anterior lumbar interbody fusion), TLIF (transforaminal lumbar interbody fusion), PLIF (posterior lumbar interbody fusion), OLIF/ATP (oblique lumbar interbody fusion/anterior to psoas) and LLIF (lateral lumbar interbody fusion); and approval to allow use of the product with titanium alloy and PEEK/titanium interbody fusion cages, as well as the original PEEK interbody fusion cages

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