Atlas FDA

IsoPSA Assay

FDA premarket approval P200048 · decided 2025-11-28

Approval details

PMA number
P200048
Trade name
IsoPSA Assay
Generic name
Multi-analyte test system with algorithmic analysis for detection of prostate cancer
Applicant
Cleveland Diagnostics, Inc.
Date received
2020-12-28
Decision date
2025-11-28
Days to decision
1796 days
Decision code
APPR
Product code
QRF
Advisory committee
Immunology
Expedited review
No
Location
Cleveland, OH
Statement
Approval for the IsoPSA Assay.The IsoPSA Assay is an in vitro test system that combines the results of total Prostate Specific Antigen (PSA) (Elecsys, Roche Diagnostics) and free PSA (Elecsys, Roche Diagnostics) from partitioned heparinized plasma into a single numerical index. The IsoPSA Assay is indicated for use in conjunction with other patient information to aid in detection of high-grade prostate cancer (Grade Group >= 2; Gleason score >= 7) in men >= 50 years of age, with total PSA levels

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