Atlas FDA

FoundationOne CDx (F1CDx)

FDA premarket approval P170019/S051 · decided 2024-01-12

Approval details

PMA number
P170019
Supplement
S051
Supplement type
Special (Immediate Track)
Supplement reason
Process Change - Manufacturer/Sterilizer/Packager/Supplier
Trade name
FoundationOne CDx (F1CDx)
Generic name
Next generation sequencing oncology panel, somatic or germline variant detection system
Applicant
Foundation Medicine, Inc.
Date received
2023-12-15
Decision date
2024-01-12
Days to decision
28 days
Decision code
APPR
Product code
PQP
Advisory committee
Pathology
Expedited review
No
Location
Boston, MA
Statement
Approval for the removal of the four variants, namely CDK12 (splice site 1047-2A>G), BRCA1 (splice site 594-2A>C), RAD54L (C391fs*1) and BRCA1 (R170Q), which are now considered as benign variants based on the evidence that the sponsor provided, from the FDA-approved CDx claims.

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