Atlas FDA

FoundationOne CDx (F1CDx)

FDA premarket approval P170019/S016 · decided 2020-06-16

Approval details

PMA number
P170019
Supplement
S016
Supplement type
Panel Track
Supplement reason
Labeling Change - Indications/instructions/shelf life/tradename
Trade name
FoundationOne CDx (F1CDx)
Generic name
Next generation sequencing oncology panel, somatic or germline variant detection system
Applicant
Foundation Medicine, Inc.
Date received
2020-01-21
Decision date
2020-06-16
Days to decision
147 days
Decision code
APPR
Product code
PQP
Advisory committee
Pathology
Expedited review
No
Location
Boston, MA
Statement
Approval order to expand the intended use of FoundationOne®CDx (F1CDx) to include high tumor mutational burden (TMB) at the cut-off of greater than or equal to 10 mutations per megabase (mut/Mb) in patients with solid tumors who may benefit from treatment with KEYTRUDA® (pembrolizumab).

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