Atlas FDA

FoundationFocus CDxBRCA

FDA premarket approval P160018 · decided 2016-12-19

Approval details

PMA number
P160018
Trade name
FoundationFocus CDxBRCA
Generic name
Next generation sequencing oncology panel, somatic or germline variant detection system
Applicant
Foundation Medicine, Inc.
Date received
2016-06-30
Decision date
2016-12-19
Days to decision
172 days
Decision code
APWD
Product code
PQP
Advisory committee
Pathology
Expedited review
Yes
Location
Cambridge, MA
Statement
Approval for The FoundationFocus CDxBRCA is a next generation sequencing based in vitro diagnostic device for qualitative detection of BRCA1 and BRCA2 alterations in formalin-fixed paraffin-embedded (FFPE) ovarian tumor tissue. The FoundationFocus CDxBRCA assay detects sequence alterations in BRCA1 and BRCA2 (BRCA1/2) genes. Results of the assay are used as an aid in identifying ovarian cancer patients for whom treatment with Rubraca (rucaparib) is being considered. If a patient is positive for

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