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Evolut PRO+ System, Evolut FX System, Evolut FX+ System

FDA premarket approval P130021/S174 · decided 2025-08-27

Approval details

PMA number
P130021
Supplement
S174
Supplement type
Panel Track
Supplement reason
Labeling Change - Indications/instructions/shelf life/tradename
Trade name
Evolut PRO+ System, Evolut FX System, Evolut FX+ System
Generic name
Aortic valve, prosthesis, percutaneously delivered
Applicant
Medtronic, Inc.
Date received
2025-02-28
Decision date
2025-08-27
Days to decision
180 days
Decision code
APPR
Product code
NPT
Advisory committee
Cardiovascular
Expedited review
No
Location
Miinneapolis, MN
Statement
Approval for the Evolut PRO+ System, Evolut FX System, Evolut FX+ System for expanding the indications to include the treatment of patients with a failed trascatheter aortic valve who are at high or greater risk of mortality from open surgical therapy. This device is indicated for use in patients with symptomatic heart disease due to failure (stenosed, insufficient, or combined) of a surgical or transcatheter bioprosthetic aortic valve who are judged by a heart team, including a cardiac surgeon,

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510(k) clearances by this applicant

RecordFirmDate
VitalFlow Set with Balance™ Biosurface (K261335)Medtronic, Inc.2026-07-31
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Clearview Intracoronary Shunts (K253998)Medtronic, Inc.2026-01-20
Bio-Medicus Life Support Catheter and Introducer (K251831)Medtronic, Inc.2026-01-15
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C320LBB Delivery System (C320LBBS45), C320LBB Delivery System (C320LBBS48), C320LBB Delivery System (C320LBBL45), C320LBB Delivery System (C320LBBL48) (K253409)Medtronic, Inc.2025-12-19