Atlas FDA

BRACAnalysis CDx

FDA premarket approval P140020/S012 · decided 2018-01-12

Approval details

PMA number
P140020
Supplement
S012
Supplement type
Normal 180 Day Track
Supplement reason
Labeling Change - Indications/instructions/shelf life/tradename
Trade name
BRACAnalysis CDx
Generic name
Cancer-related germline gene mutation detection system
Applicant
Myriad Genetic Laboratories
Date received
2017-08-31
Decision date
2018-01-12
Days to decision
134 days
Decision code
APPR
Product code
PJG
Advisory committee
Pathology
Expedited review
No
Location
Salt Lake Cit, UT
Statement
Approval for the BRACAnalysis CDx®. The device is an in vitro diagnostic device intended for the qualitative detection and classification of variants in the protein coding regions and intron/exon boundaries of the BRCA1 and BRCA2 genes using genomic DNA obtained from whole blood specimens collected in EDTA. Single nucleotide variants and small insertions and deletions (indels) are identified by polymerase chain reaction (PCR) and Sanger sequencing. Large deletions and duplications in BRCA1 and B

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