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Amplatzer™ Amulet™ Left Atrial Appendage Occluder

FDA premarket approval P200049/S012 · decided 2025-09-18

Approval details

PMA number
P200049
Supplement
S012
Supplement type
Real-Time Process
Supplement reason
Labeling Change - Indications/instructions/shelf life/tradename
Trade name
Amplatzer™ Amulet™ Left Atrial Appendage Occluder
Generic name
System, appendage closure, left atrial
Applicant
ABBOTT MEDICAL
Date received
2025-06-20
Decision date
2025-09-18
Days to decision
90 days
Decision code
APPR
Product code
NGV
Advisory committee
Cardiovascular
Expedited review
No
Location
St. Paul, MN
Statement
Approval for modifications to the Amplatzer™ Amulet™ Left Atrial Appendage Occluder Instructions for Use (IFU) and Patient Manual to remove a warning related to late pericardial effusions and to update your post implant medication regimen to include the use of oral anticoagulants.

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